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Cd4 Epitopes Hiv Vaccine

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Get the Facts
The Well Project

Understanding CD4 Cells and CD4 Cell Tests

... The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune
Ask the Experts

What is best indicator of hiv progression cd4 or cd4 %

My labs are as followsJune 08- CD4 590 VL 309 CD4% 273 months later- CD4 770 VL 2080 cd4% 263 months later- CD4 1040 VL 3000 cd4% 25.something3 months later- CD4 790 VL 444 cd% 253 months later- CD4 800 VL 3000 CD4% 24.somethingMy cd4 seems to...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...I agree with your doctor regarding your CD4 counts. Although your CD4 count is well within the normal range, your CD4% has decreased modestly. And yes, you can have a CD4% Read more »

Yellow Fever Vaccine for low CD4 count

Hello,I've been offered work in West Africa, a yellow fever hotspot. I'd like to accept this long term job but my CD4 count is 60 (but VL is now undetectable). I'm on HAART. I realize that the CDC is against this vaccination for CD4 < 200 but can...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...is generally not advised.As for the risk posed by vaccination, there is not much data in those HIV-infected individuals with CD4 counts 200 for > than 3 months on therapy and this safety has been documented in a couple of small case series. ... Read more »

HIV or Meds causing abnormal CD4 receptors?

Dr. Boyle, Do all HIV positive folk have abnormal CD4 cell receptors? If so, is this caused by HIV infection or is it a side effect of meds? How do these abnormalities manifest themselves...do they cause symptoms or compromise immune...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
...Your question is a little confusing, but I'll try to give you the answer your looking for. CD4+ T cell deficits are not present in all patients with HIV, and the time to develop signficanty immunocompromise (low CD4+ T cells) Read more »

If HIV kills CD4 cells that present themselves, can high CD4 levels in first years of infection later result in faster progression to AIDS?

Dr. Holodniy, I am searching for the right words, but have an important question:It is often assumed that the more CD4 cells in a T cell subset, the better. But,in that the more CD4's that present themselves, the more for HIV to kill, could this be...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...Not alot of studies on this issue. It is usually assumed that those infected people with such high CD4 counts, usually have low or undetectable viral loads, indicating an immune system with better capability to contain viral replication. Read more »
Articles
U.S. National Institute of Allergy and Infectious Diseases

Scientists Unveil Piece of HIV Protein That May Be Key to AIDS Vaccine Development

...researchers -- appears vulnerable to attack from this specific antibody, known as b12, that can broadly neutralize HIV. "Creating an HIV vaccine is one of the great scientific challenges of our time," says NIH Director Elias A. Zerhouni, M.D.... Read more »
Treatment Action Group

Riddle Women: Reports of Progress Toward Understanding How Some People Appear to Fight Off HIV

...as "exposed seronegative" or ESN) women convinced many skeptics that immunological resistance to HIV -- and by extension, an HIV vaccine -- is possible. Since the first description of this phenomenon by Canadian researcher Frank Plummer (at the... Read more »
The Body

The Alphabet Soup of Immune Control: ADCC Antibodies, (Memory) B-Cells, Elite Controllers and Exposed Sero-Negatives -- Will They Amount to Z?

...immune system to identify and neutralize foreign objects, such as bacteria and viruses. Epitope: An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B... Read more »
San Francisco AIDS Foundation

Status Report on HIV Vaccine Development

...evaluated until further research and trials are conducted. Fusion-Competent Vaccines HIV tries to infect any cell carrying the CD4 receptor on its surface. During infection, the viral envelope protein gp120 binds to both CD4 and a secondary,... Read more »
Connect With Others

How to increase CD4 Count?

Posted by Just_Joe, 2 Replies
...I have had HIV since November 2008 and 3-4 months later am undetectable with CD4 Count in the 200's but my last CD4 count in January 2010 is in the 300's. My doc said my ratio looks good as far as my CD4 count Read more »

Unusual case. Ongoing Low CD4 - HIV possible?

Posted by Tryin2BRational, 4 Replies
...negative/non reactive/undetectable. In June of this year, one of the physicians I was working with ordered - at my urging - a CD4 test because I thought that would give me the peace of mind I needed. Well it didn't. It came back 414 (37%) in... Read more »

does this mean you have hiv when u have this hla

Posted by need2know01, 1 Reply
...Materials and Methods Results Discussion References HIV epitopes may have developed to be poor immunogens. As a counterapproach HIV vaccine strategy, we used epitope enhancement of a conserved HIV reverse transcriptase (RT) epitope for... Read more »

CD4 CD8

Posted by Anonymous, 3 Replies
...Does anybody know what other viral infections apart from HIV can cause an inverted CD4:CD8 ratio? Read more »