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Cd4 Cell Loss In A Year

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Get the Facts
The Well Project

Understanding CD4 Cells and CD4 Cell Tests

The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune system. HIV infects and destroys a type of white blood cell called aCD4 cell (sometimes called a T-cell). As the immune system loses CD4 cells, it becomes weaker and is less able tofight off germs. When it...
Ask the Experts

Weight Loss and drop in CD4 cell on Videx/Viread

I am 42 years old and I have been living with HIV for 19 years. I am currently taking Viread, Kaletra and Videx (three years) and always take them on time. My problem is that I have lost about 40 lbs in the last 4 months with no explanation. It...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello and thanks for posting. There is an important drug interaction between Videx and Viread that may heighten toxicity and in some cases lead to a reduction in CD4 cells. Weight loss, nausea, and fatigue that develop in someone on HIV medications... Read more »

average cd4 loss per year

Dear Doctor, I read a medical research report which indicated the average annual NET loss of CD4s ( abs number),in the large majority of HIV positive people who do not take medication is approx 45. Nothing was mentioned about the average CD % drop....
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Yes, that's about right. The natural history studies would suggest about a 50 cell decline per year or about 2-3% per year. Part of the equation though relates to the viral load level, the higher the viral load, the steeper the decline. Again,... Read more »

Difference between CD4 and Percentage (CD4 count versus CD4%, 2011) (LACK OF CD4 RESPONSE DESPITE TREATMENT, 2011)

Could someone explain what exactly is the correlation between CD4 cells and percentage. I know what CD4 are but what does percentage mean. Also, I have been undetectable for 1 year now, my percentage has gone from 3 to 8 but cd4 rose to 320 from 130...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi.This gets a bit confusing, but let me try to sort this out for you. A CD4 count is not a direct cell count of CD4 cells in your blood. Rather, it's a calculation based on the total white blood cell count and the proportion of those white... Read more »

stagant CD 4 or slow increase in CD 4 cells over a few years.

could you let me know what if my CD4 still hangs around between 200 plus to 300 plus in over 5 years or more but never reaches 400 which has to meet the average of 500 to be on the safe side ? Does it mean that my body will wear out and then I will...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
If you are on HIV treatment and your viral load is undetectable, and you maintain CD4 counts between 200-300, then you are still at risk, although at a reduced level, for HIV associated complications. The risk is still greater at 200-300, then it is... Read more »
Connect With Others

To all those repeatedly neg but low cd4 (like me)

Posted by Anonymous
Dear Joel,

I've seen an expert at the the body talk about this, (Mark H.). What the hell is it. Is it just another name for an undectable strain of HIV? This is what he refers to people who keep testing negative on all sorts of test, but yet have... Read more »

To Jackie Blue - Re CD4 depletion

Posted by Anonymous, 2 Replies
Dear Jackie - thanks for replying to my post. I wanted to respond so I could answer some of your questions.

Firstly - how do I know it is not cancer - I don't - all i know is that exactly 20 days after an unprotected sexual exposure I came down with... Read more »

HELP !! CD4 170 AIDS DIAGNOSIS-- IS THIS THE END?

Posted by Anonymous, 7 Replies
I have been positive and healthy on no meds for the last 8 years. Now my cd4 count which was about 600 is down to 170 and my once undetectable viral load is now detectable. What's the average timeframe a person survives after an AIDS diagnosis ? I... Read more »

CD4 count at 8--gained weight

Posted by Anonymous, 2 Replies
Oh my I just got cd4 count at 8--down from a whopping 35 last year--freaked out my ID Doc who didn't even look at cd8 or resistance or any of that because if you're at 8 it isn't too great!

He decided to Difllucan me again on a permanent basis. He... Read more »