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Cd4 And T Lymphocytes

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AIDS InfoNet

CD4 (T-Cell) Tests

What Are CD4 Cells? CD4 cells are a type of lymphocyte (white blood cell). They are an important part of the immune system. CD4 cells are sometimes called T-cells. There are two main types of CD4 cells. T-4 cells , also called CD4+, are "helper" cells. They lead the attack against infections. T-8 cells (CD8+) are "suppressor" cells that end the immune response. CD8 cells can also be "killer" cells that kill cancer cells and cells infected...
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Total Lymphocyte Count Vs. CD4 Lymphocyte Count

Please tell me if this is correct: As HIV disease progresses the CD4 lymphocyte count decreases and the CD8 lymphocyte count increases. Because of this the total lymphocyte count (CD4 and CD8 lymphocytes together) may not decrease, but the CD4...
Douglas T. Dieterich, M.D.

Response from Douglas T. Dieterich, M.D.

New York University, School of Medicine
That is true. However overall lymphocyte counts may also decline as HIV progresses, but mostly it is theCD4. Happy Holidays Douglas T. Dieterich, M.D.... Read more »

Total Lymphocyte Count vs. CD4 Lymphocyte Count

Please tell me if this is correct: As HIV disease progresses the CD4 lymphocyte count decreases and the CD8 lymphocyte count increases. Because of this the total lymphocyte count (CD4 and CD8 lymphocytes together) may not decrease, but the CD4...
J. B. Molaghan, N.P., A.C.R.N.

Response from J. B. Molaghan, N.P., A.C.R.N.

San Francisco General Hospital
HelloYes this is essentially true. As CD4+ lymphocytes become infected with HIV, the CD4 count decreases. This causes an actual or relative increase in CD8+ cells, due to the inversion of the CD4/CD8 ratio. The total lymphocyte count may or may... Read more »

Total Lymphocyte Count Vs. CD4 Lymphocyte Count

Please tell me if this is correct: As HIV disease progresses the CD4 lymphocyte count decreases and the CD8 lymphocyte count increases. Because of this the total lymphocyte count (CD4 and CD8 lymphocytes together) may not decrease, but the CD4...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
You are correct. Except in advanced AIDS, the CD8 cells begin to go down again, and as such the total lymphocyte count will go down as well.MH... Read more »

cd4 & lymphocyte

First i want to thank you for taking the time to read our questions and reply to them. I have an issue. I have been positive for 11 yrs. I have been placed on several treatments but never followed through because of the strong side effects that i...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Your CD4 count is 300 and 15%. Your lymphocyte count is in the normal range, probably as a reflection of an elevated CD8 count, which does occur with HIV infection. My advice to you is "do not try this at home", meaning taking partial... Read more »
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IL-2 Induces Sustained CD4 Cell Increases

Posted by Anonymous, 1 Reply
IL-2 Induces Sustained CD4 Cell Increases in HIV-Infected Patients


By Deborah Mitchell

TORONTO, Sep 20 (Reuters Health) - The addition of recombinant interleukin-2 (IL-2) to an HIV antiretroviral therapy produces an increase in CD4+ T-cell counts,... Read more »

my CD4 counts dropped. is this normal?

Posted by Anonymous, 2 Replies
I have been infected for just 8 months and have been on meds. My CD4 counts rose to 416 and i am undetectable in viral load. My question is, last week, my CD4 counts dropped to 386. Is this normal? do they fluctuate? I'm worried that my meds are... Read more »

HELP !! CD4 170 AIDS DIAGNOSIS-- IS THIS THE END?

Posted by Anonymous, 7 Replies
I have been positive and healthy on no meds for the last 8 years. Now my cd4 count which was about 600 is down to 170 and my once undetectable viral load is now detectable. What's the average timeframe a person survives after an AIDS diagnosis ? I... Read more »

CD4 count at 8--gained weight

Posted by Anonymous, 2 Replies
Oh my I just got cd4 count at 8--down from a whopping 35 last year--freaked out my ID Doc who didn't even look at cd8 or resistance or any of that because if you're at 8 it isn't too great!

He decided to Difllucan me again on a permanent basis. He... Read more »