Ccr-5 Gene And Hiv

Here's a taste of what TheBody.com has to offer on this topic:

Articles

Gene Technique That Alters CCR5-Producing Gene Increases Resistance to HIV in Mice, Study Finds

Altering the gene that produces CCR5 protein on the surface of immune cells using a harmless virus was found to significantly increase resistance to HIV in mice, according to a study published Sunday in the journal Nature Biotechnology , the Press... Read more »

Case Report: Homozygous CCR5 Delta-32 Protection Overcome by Infection With X4 Virus

A sobering and important report documented the case study of a man who was homozygous for the CCR5 delta-32 mutation that generally provides effective protection against infection from HIV. With most circulating (and infectious) virus using the... Read more »

Scientists Look to Gene Therapy as Way to Boost Immune System Response to HIV

The Los Angeles Times reports on the recent efforts of scientists to use gene therapy to strengthen the ability of patients living with HIV to fight off the HIV virus. The article examines an ongoing project by a team of researchers in California... Read more »

Ask the Experts

CCR5 Delta 032 (Gene Mutation)

Dr Holodniy, I am a Hiv+ female since 2/96. My first Hiv test was done in August 1999, again in September and in November(all in 1999). Each time my vl=undetected T-cells were 1200. In February of this year(2000)I was tested againand my results were...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Thanks for the kudos. HIV requires the CD4 receptor and other "coreceptors" to gain entrance to cells and result in infection. One of these coreceptors is called CCR5. It has recently been discovered that a 32 base deletion (32 delta) in... Read more »

mutated CCR5 gene, delta 32,

Hi, I just finished watching the PBS program on the black plague amd the mutated CCR5 gene, delta 32. They stated in the program the those individuals having two copies of the mutated gene could not be infected by the HIV virus. I live in the...

Response from Ryan M. Kull, C.S.W

Columbia University's Health & Related Services

As far as I know, the general public does not have access to this sort of testing. While the research on the CCR5 mutation is important and quite compelling, it's too early to tell people that they are definitely and always immune to HIV based... Read more »

Research in HIV via CCR5 Delta 32

Hello Dr Franscino, I am curious if the following is currently being researched and if so how I could be involved. I know that scientists have recently been able to induce differentiated skin cells into a stem cell-like state using 4 genes and more...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi Patrick,No, your concept is not currently being studied and consequently no, you can not be involved. Your hypothesis is faulty on many immunological and genetic levels. You'll understand this more completely after you've been through... Read more »

CCR5

Hello everyone and thank you for everything you are doing.I found out in 2003 that I was HIV+ - I recently conduct a DNA test to found out if I have the CCR5 genotype. I hold 1 copy of the CCR5 A32 Genotype. I understand that slower the infection...

Response from Eric Daar, M.D.

UCLA School of Medicine

Thank you for your post.For others that are reading this response I will explain what the CCR5 genotype you are referring to means and then I will directly address your question.It is now known that HIV infects cells by attaching to the CD4 receptor... Read more »

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Connect With Others

Interesting article about CCR5 and HIV infection.

Posted by Anonymous, 3 Replies

http://www.newswise.com/articles/2001/8/AIDS.MHS.html

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hiv gene therapy

Posted by hopefulone, 2 Replies

hiv gene therapy has been getting a lot of play in the national and international press as of late....i would be interetested in comments on this hope. Read more »

CCR5

Posted by Anonymous, 1 Reply

Jackie, what is the mutated CCR5?? Is it a different strain or what?

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Para Doc Peru de CCR5

Posted by Anonymous, 2 Replies

En efecto Doc, me hago controles cada tres meses y controlo mi carga y cd4, por suerte y debido a mi estado cd4 700 ( 35%) no necesito de momento de medicacion...deje de fumar, hago deporte y tomo vitaminas...para asi sonseguir convertir mi... Read more »

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