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Causes Of Mitochondrial Toxicity

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Mitochondrial Toxicity

Lactic acidosis can be fatal. See your health care provider immediately if you have these symptoms. MT may also cause nerve damage (peripheral neuropathy, see Fact Sheet 555 ). It has been linked to kidney damage and hearing loss. Some researchers believe it might also contribute to fat redistribution (lipodystrophy, see Fact Sheet 553 ) in people taking antiretroviral medications (ARVs). How Do ARVs Cause MT? Mitochondria have an enzyme...
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mitochondrial toxicity

if it is thought that some nukes cause mitochondrial toxicities/deficiencies. can these problems interfere with the muscles ability for strenght and growth, ie. the ability to weight train?reason being is that I have had extensive fat loss on my...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There have been some reports of impaired/slowed muscle recovery in the setting of mitochondrial toxicity. In addition, I have cared for some patients who report and have exhibited that phenomenon. It seems to be variable and is often not seen so... Read more »

mitochondrial toxicity- what is it

Hi, Im taking 3tc, sustivia, and abacavir. Im experiencing lypo- who isnt it seems. What is mitochondrial toxicity and what caused it.Am I taking any medications which may contribute to it, and if so, some suggestions as to what else I might...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Lipodystrophy is not precisely defined but includes issues related to fat distribution (too much in some areas and loss of fat in others) and increases in blood fat levels. Some of those conditions are seen in the general population. Lipodystrophy... Read more »

How is Mitochondrial Toxicity Ruled Out?

Dear Dr. Bob,I have been HIV+ for 17 years, and on Viracept, D4T, 3TC for the past three years. My viral load undetectable, CD4's averaging 900, but I have had severe fatigue for around 9 months. I am often so exhausted that I am afraid of...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello Whipped in S.F.,Well, Ill stand by my previous statement, "we have much to learn about how to diagnose and treat mitochondrial toxicity." Is there a way to "conclusively rule it out?" Well, there are ways, but these types... Read more »

mitochondrial toxicity

Which drugs in the na class(including tenofovir)have the least about of mitochondrial toxcity VS. the most,or are they all pretty much the same?...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for the question. The issue of mitochondrial toxicity has gain a lot of recent attention. It is clear that mitochondrial toxicity is associated with lactic acidosis, pancreatitis, and certain types of muscle injury; there is conjecture... Read more »
Connect With Others

Hiv doesn't cause aids

Posted by Anonymous, 4 Replies
don't be a victim of greed , hiv doesn't cause aids and if you take those toxic drugs you will eventually die Read more »

Toxicity: Your Experiences

Posted by Anonymous
Ok.

I recently tested positive and even though my viral load under 2,000 i have a 389 CD4.

I have been investigating epivir/ziagen and viread..they might be available in a new study on a once daily dosing schedule.

My question is, what do u think about... Read more »

Is gay culture toxic?

Posted by Anonymous, 3 Replies
Everywhere you turn you see images of young, clean shaven, hairless, "buffed" boys gracing the gay mags and movies. Who actually looks like most of these people? All we are given to watch on tv is Will and Grace. They represent like 5% of the entire... Read more »

A Toxic Combination

Posted by Choosing2Liv, 9 Replies
If my dilemma was:

- just dealing with the virus; or

- just suffering with the guilt of cheating on my wife; or

- just the feelings of rejections by those who said they loved me; or

- just the constant blaming, belittlement and bursts of rage from my... Read more »