Can Maraviroc Help Me

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Get the Facts

Maraviroc (Selzentry, Celsentri)

What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US and Celsentri elsewhere) was formerly known as UK 427,857. It is a drug used for antiretroviral therapy. It is manufactured by ViiV Healthcare. Maraviroc is the first "attachment inhibitor" drug. When HIV...

Ask the Experts

Maraviroc

My viral load has become detectable and my doctor would like to put me on Maraviroc and Isentress. I have been reviewing both of these drugs and I have some concerns with Maraviroc. I know it works on the CCR5 but what is known about the CCR5...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

The CCR5 receptor is a receptor on the CD4 T cell. It is used as a 2nd (or co-) receptor for HIV to enter the T cell. HIV may also use another co-receptor (called CXCR4) to enter the cell. Since maraviroc only blocks virus that use CCR5, it is... Read more »

Viral load spike 3 weeks after stopping Maraviroc

Hello, I have been on a regimen of Truvata, Isentress, and Selzentry. I recently convinced my doctor to drop the Selzentry since no drastic CD4 increases were seen, as later studies confirmed. However, after getting my viral load tested 3 weeks...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello and thanks for posting.A single viral load of 96 could be the result of many things- including anything that causes activation of the immune system, like a cold, sinus infection, cold sore, or recent vaccination. An occasional lab error also... Read more »

Maraviroc resistance?

Hi, Carol. In May 2007 I will have completed a 96 week maraviroc study, and all I can say is that this drug is miraculous. But have you heard any buzz about developing a resistance to it? I don't get a lot of info from the study's...

Response from Carol Salisbury, APRN-BC, MSN

Michigan State University College of Nursing

Hi RLT,I am unaware of current resistance data on mavaroic. There is a resistance expert on this web site and I recommend we ask him this question. His name is Renslow Sherer. I will post your question to him. I am anxious to hear his response... Read more »

maraviroc

hi drgood morninghope all is well on your side.i am a male of 30 newly diagnosed with hiv during a blood donation camp.in couple of days my lab results for cd4 and viral load will be out and i will see an hiv specialist for the drug regimen.i read...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

There is comparativey little info about use of CCR5 inhibitors like maraviroc for initial treatment of HIV infection. Since the success rates for initial therapy with current often simple (once daily ) regimens is now fairly high (often > 90%)... Read more »

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Entry Inhibitors

Posted by Anonymous, 1 Reply

Does anyone know anything about the new entry inhibitors? I think Pfizer and Schering both have drugs in development. Should we be hopeful? Read more »

chicago,il. Alguien sabe de alguna cura para vih?

Posted by adriana, 3 Replies

hola, mi nombre es adriana y auque tengo viviendo con el virus 4 anios en realidad no tengo mucha informacion creo q por no querer pensar demaciado en este virus lo hice a un lado, claro sin dejar de cuidarme.
me gustaria saber si alguien de ustedes... Read more »

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Posted by TheBody, 124 Replies

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