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Can Darunavir Help Me

Here's a taste of what has to offer on this topic:
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Darunavir or not to Darunavir + Low WBC

Hi Joe,I have another question for you. I have recently seen my consultant, and he has suggested changing PI's from Atazanavir to Darunavir. He quotes a few studies that suggest additional benefit for DRV. At the moment I'm undetectable on...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Michael,Thanks for your questions. Darunavir is now approved for both first line treatment as well as for treatment experienced patients. It is a very potent protease inhibitor, but potency does not seem to be an issue with your regimen since you... Read more »

Darunavir Cross Resistance

35yo male, healthy, HIV positive (VL stable over the last years @ 25k, CD4 has always been between... Read more »

Co administration of darunavir and Atazanavir

Dr Dr,I have been on this regimen (1200 mg Prezista + 100 mg norvir and 300 mg Reyataz) for more... Read more »
Canadian AIDS Treatment Information Exchange

Darunavir-Ritonavir Monotherapy: Impact on Fat and Bones

Darunavir is a powerful protease inhibitor. In a previous trial called Monet , results showed that switching to darunavir-ritonavir monotherapy from standard triple therapy (ART) is roughly as effective as ART. The Monarch Study In a substudy... Read more »

Darunavir Matches, and in Some Patients Outperforms, Lopinavir/Ritonavir as Second-Line and Third-Line Treatment

Darunavir (TMC114, Prezista) is the first engineered protease inhibitor (PI) designed specifically to overcome PI-resistant mutations. At the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2007), several... Read more »
Canadian AIDS Treatment Information Exchange

Surprising Changes in Body Fat With Darunavir Monotherapy

Exposure to the nukes d4T (stavudine, Zerit) and, to a lesser extent, AZT (zidovudine, Retrovir) can cause the loss of subcutaneous fat (the fatty layer just under the skin). The wasting away of this fatty layer is called lipoatrophy. This wasting... Read more »
Being Alive

Darunavir/Ritonavir and Etravirine as a Prevention Method Is Biologically Plausible

A pharmacokinetic study suggests that ritonavir-boosted darunavir (Prezista) and etravirine (Intelence) achieve high concentrations in semen and rectal tissue, and could therefore help avert HIV transmission and infection, especially in gay men.... Read more »
Connect With Others

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother.
My son and daughter-in-law seem not to... Read more »

anal problems....

Posted by erik1964
I have been on hiv medication for more than 10 years now, I noticed that Viramune gives me no anal pleasure any more (but also did Darunavir). Because of the side effects I don't have lots of choices for therapy. Now I am on Truvada (really good... Read more »

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting.

I have just spoken to my son again. He was finally able to convince his... Read more »

New Drug - TMC114

Posted by Survivor, 1 Reply
Don't Let TMC114 Cost More Than Kaletra, Advocates Urge

We may be only days away from an announcement that the U.S. has approved a
new HIV medication: TMC114 (darunavir), a protease inhibitor that may be
especially helpful for people with... Read more »