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Atripla And Prozac Interaction

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Get the Facts
AIDS InfoNet

Atripla (Efavirenz + Emtricitabine + Tenofovir)

What Is Atripla? Atripla is a tablet that contains three antiretroviral drugs (ARVs) used to fight HIV: efavirenz (Sustiva), emtricitabine (Emtriva), and tenofovir (Viread). Atripla is manufactured by Gilead and Bristol-Myers Squibb. It is the first tablet that includes a complete antiretroviral regimen. A generic version was approved for sale outside the U.S. under the PEPFAR program (see Fact Sheet 475 ). The drugs in Atripla are a...
Ask the Experts

Prozac Interactions with HAART

Dear SirI am going to take HAART soon. My first regimen is AZT, 3TC, Nevirapine. I am also taking antidepressants Prothiaden (Dosulepin). If that does not work, then on Prozac. I am extremely keen to know if these drugs interact with my HIV drugs or...
Ewald Horwath, M.D.

Response from Ewald Horwath, M.D.

University of Miami School of Medicine
Prothiaden is in the class of tricyclic antidepressants. These drugs are primarily metabolized by a certain enzyme (CYP450 2D6) that interacts with ritonavir, which inhibits the action of this enzyme. The combination of ritonavir (or other 2D6... Read more »

Prozac & Wellbutrin

i recently started taking prozac a week ago which was added to wellbutrin sr 150mg. i was fine for the first week, lots of energy, and then all of a sudden i start feeling very tired and almost comatose, like a drugged feeling. i would lay down at...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
You don't provide any details regarding your HIV status or which HIV meds you are on (which could interact with your other meds). What you describe can happen with Prozac but would be somewhat unusual unless there are other factors (other meds... Read more »


Dear Dr. Young, am referring to my question and your answer (below). I forgot to include REYATAZ in my list of meds, which is part of my current regimen. Would your answer still be the same or are there any known interactions between REYATAZ and...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and good to hear back from you.Yes, it is ok to take the Prozac with the atazanavir (Reyataz)-based HAART.Be well,BY... Read more »

Risperidone and Atripla interaction

Dear doc is there any interaction between risperidone and Atripla?...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is a potential interaction between risperdal and efavirenz (in Atripla) that could lead to decrased effectiveness of the risperdal (sometimes dose adjustment with input from pharmacist can compensate for that). KH... Read more »
Connect With Others

For those on the Atripla regimen

Posted by Pos_in_Thailand
I am giving a URL for a very interesting and complete drug interactions database. If you are on Atripla, and are on or will be needing to take any medication for any reason, you can type it's name in the search and see if there is a known... Read more »


Posted by tuffnftl, 3 Replies
hey guys i just started the new drug atripla, any advice, help scared to death of new things open to suggestions Read more »

Solution to Atripla Side Effects (at least for me)

Posted by Wiilock, 3 Replies
Hey all, I have been on the "wonder pill" for about 3 years now. Previously was on norvir boosted invirase/truvada combo but the GI problems finally were too much.
Anyway I want to briefly recap what I've learned from some of my homeopathic... Read more »

switched to Atripla! wooohoooooo

Posted by mauka, 3 Replies
Man I was pretty worried but I guess so far so good, no nightmares, dreaming a lot yes but it ain't bad at all! The only thing is when i go to bed I get so itchy on my feet and legs and scratch almost to bleed any tips on that? Thanks everyone for... Read more »