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Atazanavir Prescribing Information

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AIDS InfoNet

Atazanavir (Reyataz)

What Is Atazanavir? Atazanavir, also called Reyataz, is a drug used as part of antiretroviral therapy (ART). Atazanavir is a protease inhibitor manufactured by Bristol-Myers Squibb. Atazanavir was approved by the FDA in 2003. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Protease inhibitors prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV...
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Atazanavir

I reside in Sydney, Australia and have a brief question regarding Atazanavir.I am aware that it is new and that there is not a lot of information out there on it and hope that you might be able to assist.Gas, yes Gas!. Lots of it, farting, burping...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
This is, indeed, a new drug and all the information is not in on it. In the clinical trials, the side effect that you describe occurred in <3% people on Atazanavir (although the incidence was not zero). Are there any other drugs you are taking... Read more »

Atazanavir

Will Atazanavir not cause lipo as have other PI's? What about Tripranavir? Do you think we can create combo's that do not cause lipo?...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
That is one of the most important questions we're currently confronting regarding HIV therapy. Unfortunately, at this point we don't have an answer, although some studies indicate that the risk of lipodystrophy is lower in non-nucleoside... Read more »

interaction between sibutramine and atazanavir

I would like to know about the potential interaction between atazanavir and this lowering-weigth agent ( sibutramine) since both of them are metabolized by the same enzyme. Thank you...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
I have not seen a study formally looking at the potential interaction between atazanavir and sibutramine. You are correct that both are metabolized in the liver. I think the concern is more whether there may be increased toxicity from the... Read more »

Atazanavir and Omeprazole

Hello Dr. Keith. I've been having major problems due to GI conditions. I have intense heartburn, even chest pain. I've had an endoscopy done and they found erosions in stomach and duodenum, also irritation of the esophagus. On top of that...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is concern that the reduced stoamch acid from the omeprazole will decrease the absorptio/blood levels/effectiveness of the atazanavir. Separating the omeprazole by 12 hours from the atazanvir and using the 20 mg/day max may allow the drugs to... Read more »
Connect With Others

need atazanavir

Posted by princealbert
Does anyone know how to access atazanavir, a new protease inhibitor not yet approved? I've got less than 20 CD4, VL 40,000, am multi-drug resistant, and don't have too many options left. I might be getting T-20, but need another good drug to add to... Read more »

Need Atazanavir

Posted by princealbert, 1 Reply
Does anyone know how to access atazanavir, a new protease inhibitor not yet approved? I've got less than 20 CD4, VL 40,000, am multi-drug resistant, and don't have too many options left. I might be getting T-20, but need another good drug to add to... Read more »

Those taking, Raltegravir, Truvada & Atazanavir

Posted by sweetvanilla27, 1 Reply
I am wanting to hear from anyone who have experienced taking Raltegravir, Truvada & Atazanavir and how you have got on with the meds?

I first started taking meds in May this year I was put on Truvda and Sustiva first, and was taken off them due... Read more »

information

Posted by Anonymous, 1 Reply
Exploring: NIAID, NIH, U.S. DHHS

March 2005
HIV Infection and AIDS: An Overview
INTRODUCTION
AIDS (acquired immunodeficiency syndrome) was first reported in the United States in 1981 and has since become a major worldwide epidemic. AIDS is caused by HIV... Read more »