Are Cd4 Cells Cytotoxic In Function

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Understanding CD4 Cells and CD4 Cell Tests

The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune system. HIV infects and destroys a type of white blood cell called aCD4 cell (sometimes called a T-cell). When the immune system loses too many CD4 cells, it becomes weak and isunable to fight off germs. At...

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Absolute CD4 count down while CD4% up. (ABSOLUTE CD4 COUNT VERSUS CD4%)

Hello Dr. Bob,You are wonderful and doing very important job :) . I have never seen such a Doctor who has an excellent sense of humor and plays the piano. Btw, I play the cello :) . Now my question. My time of infection is between 2006 02 and 2006...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello Cello-Guy,I strongly disagree with the advice your doctor gave you regarding absolute CD4 counts versus CD4%! I reviewed this topic in detail recently in this forum. Consequently, rather than retyping the same information, I will instead... Read more »

CD4 Count V. CD4% Count (ABSOLUTE CD4 COUNT VERSUS CD4%, 2010) (WHEN TO START TREATMENT, 2010)

Hi,I was diagnosed with HIV around 15 months ago. Since then my health has been good (especially in the last six months) but my CD4 count has fallen a bit rapidly from 470 to 371 to 324 over this time period. However, my CD4 percentage count has...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,You are correct: The CD4% is generally considered the more accurate indicator of immune integrity, as it doesn't tend to fluctuate as much due to intercurrent illnesses and other non-HIV-related factors. (See below.)Regarding beginning... Read more »

how do depleted numbers of CD4 cells affect antibody production

and cell mediated immunity?what affect do antibodies have on the numbers of HIV particles?thanks...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

CD4 cells make lots of chemicals and hormones that are required for normal function of b cells and cytotoxic t cells (CD8 cells). Thus, if their number is decreased significantly, these other cells are not signalled appropriately to perform their... Read more »

Re : Low CD4 Absolute but High CD4

Thanks for the answer. My total WBC was 6000 and total lymphocyte was 2256 but I didn't go for VL count since I couldn't afford for it. Anyway I had it done recently and will let you know soon.Coulod you please tell me if the OIs are...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Yes, development of OIs are a function of the degree of immune suppression and CD4 counts are a direct reflection of that.... Read more »

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RE: CD4 up!

Posted by asianboy, 1 Reply

I was tested positive last December 2010 (CD4=11), and was utterly devastated. My whole world came to a halt --- career, plans, everything. I thought that was the end of it.
In my recent blood test, my CD4 is now up to 88. I could've never been... Read more »

Newly diagnosed, but CD4 counts is only 60!

Posted by Anonymous, 5 Replies

I have been unwell since this spring. After a series of lymph nodes problem, I went to have myself tested. Three weeks ago I learned that I was positive. Last week had my first HIV doctor appointment and did some blood works. Today I found out that... Read more »

What is a T-Cell or CD4 Count?

Posted by TheBody

What Is a T-Cell or CD4 Count?

Your T-cell count, also known as a CD4 count, reveals the number of T cells in your body. A T cell is a special kind of white blood cell, and the more you have, the stronger your immune system is. When you were infected... Read more »

IL-2 Induces Sustained CD4 Cell Increases

Posted by Anonymous

IL-2 Induces Sustained CD4 Cell Increases in HIV-Infected Patients

By Deborah Mitchell

TORONTO, Sep 20 (Reuters Health) - The addition of recombinant interleukin-2 (IL-2) to an HIV antiretroviral therapy produces an increase in CD4+ T-cell counts,... Read more »

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