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Are Cd4 Cells Cytotoxic In Function

Here's a taste of what has to offer on this topic:
Get the Facts
The Well Project

Understanding CD4 Cells and CD4 Cell Tests

...fighting germs and infections.White blood cells are an important part of your immune system. HIV infects and destroys a type of white blood cell called aCD4 cell (sometimes called a T-cell). When the immune system loses too many CD4 cells, it becomes weak and isunable to fight off germs. At this point, you are at risk of gettinginfections, called AIDS-related opportunistic infections (OIs), which can cause serious illness ordeath. The...
Ask the Experts

increased risk of cancers-- what's more important CD4 cells or natural killer cells?

I read that, in HIV treatment, CD4 levels are the main way to monitor the condition of the immune system and risks of diseases/Kaposi's Sarcoma. But, I see other comments about natural killer cells and that they help suppress cancers. Is there a...
Bruce Dezube, M.D.

Response from Bruce Dezube, M.D.

Harvard Medical School
...which determines one's risk for cancer. The immune system is very complex and many elements of the system (including natural killer cells) help determine one's risk for developing cancer. This would explain why some patients have aggressive... Read more »

CD 4 & CD 8

Hi Doc, what's up. I have question on CD 4 & 8 My recent Blood test says CD 4 is 363 and CD 8 is 1350 what will be effective in my body whith these Numbers, I have didagionsed HIV 2 in 03 and taking Rayataz,Atripla and Istress. your reply will solve...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...counts will go down with untreated HIV infcetion. Usually more slowly with HIV-2 infection, than with HIV-1. Cd8 or T-suppresor/cytotoxic cell numbers tend to increase during HIV infection (eventually declining as well with later stages of... Read more »

how do depleted numbers of CD4 cells affect antibody production

and cell mediated immunity?what affect do antibodies have on the numbers of HIV particles?thanks
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...CD4 cells make lots of chemicals and hormones that are required for normal function of b cells and cytotoxic t cells (CD8 cells). Thus, Read more »

Responsiveness of CD4 Cells

Thank you for the most amazing information you provide to people all over the worldeven to us here in Cape Town, South Africa.I understand that CD4-cells counts are hugely affected by various factors such as stress levels, opportunistic infections,...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Demyan,Thanks for your post and question. It's great to know that we're reaching readers in South Africa.CD4 cell levels, as part of the immune system, can respond quite quickly to immunologic stimulus. Their overall levels fluctuate a lot, Read more »
AIDS InfoNet

CD4 Cell Tests

... What Are CD4 Cells? Why Are CD4 Cells Important in HIV? What Is a CD4 Test? What Factors Influence a CD4 Cell Count? How Are the Test Results Read more »
Treatment Action Group

Dendritic Cells in Drag: Inauspicious Debut for HIV Specific CTLs; New Concerns about IL-12; Neutralizing Approaches for "Bad" Cytokines; Parke-Davis Targets Cellular Factors

...proliferation in vitro. Both cytokines synergize with IL-12 to induce increased IFN-gamma expression, and both induce natural killer cell activity. IL-15 does not, however, stimulate resting T-cells in the way that IL-2 can in higher... Read more »
Canadian AIDS Treatment Information Exchange

The Immune System

...virus-infected and cancerous cells, both in response to CD4+ cell signals and on their own, without direction from other lymphocytes. NK cells are important in the regulation of lymphocytes and other immune cells and, although they have been far... Read more »
The Well Project

Understanding the Immune System

...important components of the immune system are: Dendritic cells and macrophages T cells Killer T cells Natural killer cells B cells Neutrophils Dendritic Cells and Macrophages Dendritic cells and macrophages are... Read more »
Connect With Others

Read the stories but I think I'm still +

Posted by Anonymous, 5 Replies
I've read all the uplifting stories and still cant stop thinking I'm positive as well as some of my family members. I've posted before so some of you may rememeber. My risk was slight oral exposure (on her) to a stripper that was from Russia. It... Read more »

What is a T-Cell or CD4 Count?

Posted by TheBody
What Is a T-Cell or CD4 Count? Your T-cell count, also known as a CD4 count, reveals the number of T cells in your body. A T cell is a special kind of white blood cell, and the more you have, the stronger your immune system is. When you were... Read more »


Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

CD4+Tcell count indicative of nothing.

Posted by TonyF, 4 Replies
This, rather than being a myth the public promotes, could be considered a myth that the medical establishment promotes. We are led to believe that our bi-yearly doctor checkup of our CD4+Tcell count is a good baseline determination of where we... Read more »