Amino Acid In The Hiv Protease Active Site

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dietary protease vs HIV protease

My mother who is a dietician feels my regimen of Kaletra, Invirase and Truvada is interfering with fat absorption. She feels this is why PI's seem to result in smelly or loose stools. Her solution, dietary enzymes which contain the...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

What you are describing is a combination of enzymes produced by the pancrease to facilitate digestion and absorption of food from the gut. If there is pancreatic insufficiency then those enzymes are given in pill form and that is often helpful. I... Read more »

Medication reaction with amino acid supplements

After about a year of taking weight lifting supplements, I figured out some "problems" I had were related to something in these supplements and the meds I take. Well, a safe presumption.I am on Reyataz, Viread, 3TC, Norvir. Very well...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Thanks for sharing your experience. I would agree that one has to be generally cautious and on guard for unexpected drug interactions when on antiretroviral therapy. I am not aware of specific problems that have been reported when using protease... Read more »

HIV protease inhibitors

Could you tell me the spectrum of activity and the mechanism of resistance for the antimicrobial HIV protease inhibitors (Ex: Indinavir)and do they work with gram positve/gram negative bacteria. What bacteria does it work against. Or what sites I...

Response from Eric Daar, M.D.

UCLA School of Medicine

The HIV protease inhibitor selectively blocks the protease enzyme and prevents an infected cell from producing infectious HIV. Resistance develops when mutations emerge in the viral protease enzyme that prevent the inhibitor from interacting with... Read more »

Amino Acids and AIDS meds

This probably isn't suitable for posting; however, as a follow-up, I found an article about this issue which I originally asked about, that may point in the right direction:http://health.families.com/drug-metabolisminteractions-1101-1104-gemIt...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Thank you for the follow-up information. KH... Read more »

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HIV+ Male Makes Web Sites To Meet Other POZ

Posted by Anonymous, 3 Replies

Hi there, since 1998 I have been making websites for the "POZ COZ". I even met my girlfriend through my sites!

I make the sites without an income yet I do not charge for my services, it's been a tough go as I am a poor guy and been homeless many... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol

Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

Beware of scam operators of HIV+ dating sites!

Posted by Anonymous, 2 Replies

I have been following the recent revelations of the scandal of match.com and yahoo personals being sued by "paying customers" who allege both these well known and very non HIV+ dating sites were using a very common technique too lure in paying... Read more »

Beware of scam operators of HIV+ dating sites!

Posted by Anonymous

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