Adverse Reaction To Fusion Inhibitors
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University of Minnesota, School of MedicineT-20 = Fuzeon is the only fusion inhibitor soon to be more widely available. Since it acts outside of cells (blocking fusion) its toxicity would be expected to be low and that has been the case in major clinical trials conducted to date. The major... Read more »
Rocky Mountain CARESThanks for your question.Fusion (or entry) inhibitors should make their debut in the near future with the release of enfuvitide (nice name, huh--otherwise known as Fuzeon or T-20). The class of medications is exciting from the perspective that many... Read more »
University of South Florida School of MedicineFuzeon is the only fusion inhibitor currently approved by the FDA. Fusion inhibitors are part of a bigger classification of drugs called entry inhibitors which also includes attachment inhibitors, CXCR4 inhibitors and CCR5 inhibitors. There are... Read more »
University of Minnesota, School of MedicineT-20 (the only fusion inhibitor in wide use) has not been associated with lipodystrophy yet. Since it works extracellularly there is hope that some of those problems associated with unwanted activity of a drug inside cells might be avoided. It... Read more »
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Posted by AnonymousDoes anyone know if the fusion inhibitor trials (phase III) are going OK, or where to go for an update? Last I heard 700 patients in 100 countries were in the study for T-20(?)
I went to the Trimeris site and didn't see anything new.
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