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Adefovir Tenofovir

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AIDS InfoNet

Tenofovir (Viread)

What Is Tenofovir? Tenofovir (Viread), also called bis-POC PMPA, is a drug used as part of antiretroviral therapy (ART). It is manufactured by Gilead Sciences. The FDA approved tenofovir for use against HIV in October 2001. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Tenofovir is a nucleotide analog reverse transcriptase inhibitor, or nuke. These drugs stop HIV from multiplying by preventing the reverse...
Ask the Experts

next to tenofovir?

dear doc, first we got adefovir which is now used only in hepa B. then came tenofovir. but we have not heard any congener to tenofovir without any cross resistance. why so?regards....
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hi and thanks for posting.There is a prodrug congener of tenofovir, called GS-7340 in development. As a prodrug, it has the same active molecule as tenofovir DF and shares the same resistance profile. GS-7340 is in phase 3 clinical studies.Other... Read more »

Sub-optimal response with Adefovir.

I have been on Adefovir (10mg) for the past 6 monts and I just read an article on this. I wanted to know if I fall in to this category beacuse of suboptimal response. Can you please comment on the article at the link...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
It would be reasonable to discuss switching to entecavir (Baraclude) with your physician. Entecavir is more potent in terms of reducing viral load. It has similar efficacy in terms of seroconversion as lamivudine. It has not been compared... Read more »

what adefovir can cause to the embryo

Dear Doctorsi ve being taking adefovir about a year and a half , since i developed lamivudine resistance. the results are good, and the test blood are normal. my viral load went from 180.000 copies to now 2.280 copies with HBV DNA QNT PCR ( pg/ml)...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
Adefovir is listed as a "category C" drug for pregnant women. That means that the drug should only be used in pregnant women if necessary since there are no studies in pregnant women of this drug. Studies in rats and rabbits are... Read more »

Anti-Hbs is also getting low while taking Adefovir

Is it normal that while my HBsAG is getting lower , My Anti-Hbs is alo getting lower.While taking Adefovir, Is this bad ?before adefovirHBSAG 0.048 -3.500ANTI-HBS 10.0-0.9while with adefovirHBSAG 0.056 -3.272ANTI-HBS 10.0-0.33 months on...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
There numbers appear to be ranges for the laboratory and not necessarily reflective of your results, which are usually expressed as a single number. The main thing to follow is HBV DNA - I don't see a result before treatment so cannot comment.... Read more »
Connect With Others


Posted by Anonymous, 1 Reply
I'm just starting treatment and my doctor who does things differently recommended tenofovir...I know it's a new drug. Has anyone any experience with it?

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HIV testing while on tenofovir.

Posted by EmeandEme, 1 Reply
I have been taking tenofovir for over 6 months for Hep B. 3 months ago I had unprotected sex because the condom broke and need to figure out what test I need to take to check for HIV.

I have gotten tested every single month and everything has come... Read more »

Complera, the new once-daily combo pill

Posted by bartleby
new treatment option. here's what you need to know.
Complera (rilpivirine/tenofovir/FTC) is like Atripla (efavirenz/tenofovir/FTC) except it replaces the Sustiva (efavirenz, Stocrin) arm with Edurant (rilpivirine). it has to be taken with a meal.... Read more »

Shortness of breath

Posted by garret99
Hello everyone. I would like to know if there is anyone out there that is using stochrine,epivir and doc removed one of my meds and replaced it with the epivir. After 3 months my cd4 count went from 155 to 260 and my viral load was... Read more »