Advertisement

The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol

Active Site Of Hiv-1 Protease

Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
Project Inform

Tesamorelin and Excess Deep Belly Fat

Introduction Body Shape Changes Study Volunteers Study Design Side Effects Study Results Project Inform's Perspective Introduction Studied as a way to reduce excess deep belly fat, the synthetic human growth hormone releasing factor called tesamorelin may be approved by the FDA in the first half of 2010. Results from a 52-week study of 816 people showed 18% less deep belly fat in those on tesamorelin than those...
Ask the Experts

ARVs Resisrance

Hi Dr. i am a pharmacy professional working in ART clinic in ethiopia. i need to now if there are any updates with related to resistance and the basic mechanism for hoe the PI groups will make resistance.additionaly can you tell me about codons?...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
I am happy to refer you to several excellent web sites that deal more comprehensively with the mechanisms of resistance, and with ongoing research into resistance to ARTs, than this site.First, I suggest the IAS-USA Drug Resistance Mutationa Group... Read more »

Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation.

What do you think of the research of Siliciano and Pomerantz ? HIV-1 latency in resting CD4+ T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy (HAART). Eliminating the latent HIV-1 reservoir...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for your post.It's a very long way from early clinical science to a drug, never mind being "very close to the cure". Even for less revolutionary discoveries, it can take many years of testing and clinical trials to establish... Read more »

Exercise and HIV

Nelson, is there any documented research that shows that regular exercise keeps the onset of AIDS in check for longtime survivors of HIV who strictly adhere to their medication regiment. I am 55 y/o, have been positive for 17 years, and in the best...
Nelson Vergel, B.S.Ch.E., M.B.A.

Response from Nelson Vergel, B.S.Ch.E., M.B.A.

Program for Wellness Restoration
Like you, I am also a 25-year survivor who started working out right when I was told I was poz. I was told "Go home, eat well, pray, put your "things" in order and take care of yourself" in 1986 when I got my test results after recently arriving to... Read more »

drug-protease mechanism

What are the key biochemical features of the drug-protein interaction that allows it to function as a protease inhibitor?
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...They bind to the active site of the protease enzyme so the HIV polyprotein is not allowed to enter the active site and be cut into smaller pieces by the protease. Read more »
Articles
AIDS Project Los Angeles

Combating HIV with good nutrition

... Theory In a report in the June 20 edition of The Lancet , Cooper and Carr hypothesize that lipodystrophy occurs because HIV-1 protease inhibitors have a high attraction for the active site of the HIV-1 protease, which may be similar enough in... Read more »
AIDS InfoNet

Protease Inhibitors in Development

Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors... Read more »
Test Positive Aware Network

Fuzeon

Common Name: enfuvirtide or T-20 Brand Name: Fuzeon Class: HIV fusion inhibitor (a type of entry inhibitor) Standard dose: One subcutaneous (under the skin) injection of 90 mg (1 ml) twice daily (every 12 hours) into the upper... Read more »
AIDS InfoNet

Drug Use and HIV

How Does Drug Use Relate to HIV? Injection and Infection Access to Clean Needles Drug Use and Unsafe Sex Medications and Drugs The Bottom Line How Does Drug Use Relate to HIV? Drug and alcohol use is a major factor in the spread... Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law seem not to... Read more »

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

Excessive Mastubation

Posted by Anonymous, 5 Replies
Ever since I found out that I'm poz, I've been spending a lot more time mastubating. Is that normal? Or could it be because of the amount of time I've been spending reading posts about sexual issues? Pleasing myself has become an every day thing... Read more »