Abacavir Dosage

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Get the Facts

Trizivir (Zidovudine + Lamivudine + Abacavir)

What Is Trizivir? Trizivir is a pill that contains three antiretroviral drugs (ARVs) used to fight HIV: zidovudine (Retrovir, AZT), lamivudine (Epivir, 3TC) and abacavir (Ziagen). Trizivir is manufactured by ViiV Healthcare. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 925 ). The drugs in Trizivir are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the reverse transcriptase...

Ask the Experts

abacavir

Dear Doctor,How can I find out if the maker of abacavir has any intentions of producing this drug in a higer dosage so that I will be able to take fewer pills. Currently I'm taking 4 in the morning and 4 at night.Thanks...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Compacting more drug into a single pill is a simple, and attractive way to simplify a drug regimen (similar to recent drug programs for efavirenz and delaviradine). I am not aware of any plans from GlaxoSmithKline in making higher dose pills of... Read more »

Adjust Abacavir dose with Kaletra?

Is it true that Kaletra will lower blood levels of abacavir? If so, should an adjustment be made to the abacavir dosage? Thanks....

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

There is no dose change of abacavir with Kaletra that I am aware of.In general, Kaletra, a combo PI that contains a small amount of ritonavir, will inhibit the activity of an enzyme that metabolizes many of the other PIs. This means that if... Read more »

Agenerase Dose w/ Delavirdine & Abacavir

Dear Dr. Cohen,Having been on nearly every drug available for the past 11 of my 42 years, my most recent geno and phenotypes show that my least resistance is to the drug combo of delavirdine/agenerase/abacavir. I had been on AMP/ABV/EFV since my...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Well, Paul, Congrats on first doing your homework. Here are a few thoughts to add.First - the tenofovir expanded access recently expanded - now anyone with any CD4/viral load may be eligible - so this is again an option. Whether you should play... Read more »

Loss of fat in buttocks possibly due to Abacavir?

I'm currently taking Sustiva, Videx, and Abacavir. I was switched to Abacavir four months ago from Zerit after experiencing Lactic Acidosis. I soon noticed that my buttocks had shrunk and my doctor said it was probably from the Zerit and that...

Response from Alvan Fisher, M.D.

Brown University School of Medicine

Wish we knew the answers. Any antiretroviral may be associated with fat wasting; especially the nucleosides. You have taken zerit, videx and abacavir: all nucleosides. We do not know why this occurs, why this occurs in some but not others, why some... Read more »

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Abacavir,viramune,viread

Posted by Anonymous, 2 Replies

I'm on day 4 of my new combo Abacavir,viramune,viread, epivir and it totally sucks. I feel lousy all of the time. Is this typical when starting this combo? This is my 4th combo since diagnosis...

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AbacavirLamivudine to treat HIV infection.

Posted by jenniferdraper

AbacavirLamivudine is used to treat HIV infection. This combination medication is used with other medications. It belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors. Read more »

Aetna & Ziagen aka Abacavir

Posted by wtxgringo, 1 Reply

So now Aetna has switched over to a generic form of Abacavir from the brand name Ziagen and while I've been getting the Rx for over 6 years from Aetna RX Home Delivery, this months refill was cancelled with the note that Abacavir is now a... Read more »

Abacavir - Hypersensitivity - EPZICOM

Posted by Survivor, 2 Replies

David, I read your Email and brought the PDF forward. Dr. Ben was very watchful when I initially got started and had follow up calls to me regarding any problems if in deed I was blinded on the Abacavir. Either I am on it and am fine or I am not... Read more »

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