A Guide To HIV Drug Resistance

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Articles

A Guide to HIV Drug Resistance

Order This Booklet -->To view other booklets from TheBody.com, click here . C O N T E N T S Why Is Understanding Drug Resistance Important? How HIV Works HIV Mutations HIV Treatment How Drug Resistance Occurs How Does... Read more »

ICAAC 2007: Key HIV Research on HIV/HAART Complications and HIV Drug Resistance

This is part three of a three-part article. For part one, First-Line Therapy, click here . For part two, Antiretrovirals in Development, click here . Listening and Viewing Options Full Interview and Slides Podcast of Interview ... Read more »

Canadian AIDS Treatment Information Exchange

A Practical Guide to HIV Drug Treatment for People Living With HIV

Table of Contents Acknowledgments and Credits Getting Started How to Use This Guide Living With HIV, Living With Treatment: The Capsule Version HIV and AIDS: The Basics The Immune System What Does HIV Do to You? Monitoring... Read more »

Ask the Experts

Resistance (TWO HIV POSITIVES, 2009)

Hello Robert,I met a guy and we are both HIV+ him 23 years and me 7 years.His CD4 is 155 and Viroload is undetectable on treatmentMy CD4 is 528 and Viroload is 3547 no treatmentHis virus is resistant to 90% of all medicine.My virus show hardly no...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,I actually have addressed this topic many, many times before. (See below for a sample of what can be found in the archives of this forum!)Can you acquire a second, more aggressive and drug-resistant strain of virus? Yes, this is unfortunately... Read more »

hiv drug discovery from high speed supercomputers and drug resistance

As you already know, President Obama set aside approx $126 million in this years budget to develop next generation exascale supercomputers. Due to the fact that supercomputers have an unlimited potential to help find solutions to serious problems,...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hi Steve,I and all other folks with common sense would support investments in science, research and technology (rather than war and tax cuts for billionaires). Unfortunately the Republicans don't see it that way. Their budget cuts are... Read more »

Are the undetectable viral copies more prone to being drug resistant and spawning many drug resistant viral copies?

Commercial assays only detec >50 copies of plasma VL. Is it possible/likely (?) that the <50 copies of virus may be the ones that are drug resistant?What are the reservoirs where dormant HIV resides and does the virus continue to do damage...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

Commercial assays only detect the majority species, so we are unaware of the mutations present on minority species, i.e. those with < 10-20% of the population. More sophisticated techniques have been developed which can detect resistance down to... Read more »

Are the undetectable viral copies more prone to being drug resistant and spawning many drug resistant viral copies?

Commercial assays only detec >50 copies of plasma VL. Is it possible/likely (?) that the <50 copies of virus may be the ones that are drug resistant? What are the reservoirs where dormant HIV resides and does the virus continue to do damage...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Given those numbers, you are not only immunologically intact, but cognitively as well. There may be areas of low level replication going on despite a plasma viral load < 50. Plasma viral load is only a measure of circulating virus being produced.... Read more »

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Connect With Others

Drug Resistant HIV

Posted by Anonymous

Hi

I just found out the strain of hiv i have is resistant to possibly a whole class of NRTIs and PIs..any experience with this for any of you? what could the options be for someone in my situation? I am still treatment naive.

Read more »

New York draws fire over case of drug-resistantHIV

Posted by Anonymous

Nature 433, 788 (24 February 2005)

New York draws fire over case of drug-resistant HIV

ERIKA CHECK

Rare, aggressive form of AIDS used to publicize dangers of unprotected
sex.

[WASHINGTON] A decision by New York health officials to announce the
detection... Read more »

Resisting Resistance - A Story

Posted by Survivor, 1 Reply

Personal Perspective: Resisting Resistance

By Matt Sharp

Spring 2006

In a little over four months I will turn fifty. When I was diagnosed with HIV in 1988 I never dreamed I'd reach forty. I've survived a long battle with HIV, and it has not been... Read more »

Resistant, then what? How many lines of therapy?

Posted by Anonymous, 3 Replies

What percentage of folks infected with HIV are basically screwed by total resistance right out of the gate? I know resistance forms of HIV is becoming more common, but generally there is still a line of treatment options that will work for these... Read more »

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