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Trizivir Dosages

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AIDS InfoNet

Trizivir (Zidovudine + Lamivudine + Abacavir)

What Is Trizivir? Trizivir is a pill that contains three antiretroviral drugs (ARVs) used to fight HIV: zidovudine (Retrovir, AZT), lamivudine (Epivir, 3TC) and abacavir (Ziagen). Trizivir is manufactured by ViiV Healthcare. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 925 ). The drugs in Trizivir are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the reverse transcriptase...
Ask the Experts

trizivir or trizivir plus viramune

Last month, blood tests show a blip 50 instead of less than 40 on trizivir alone after being undetectable for 2 years. My doctor recommended adding viramune to preclude possible resistance with trizir alone. Please advise!...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
The use of trizivir alone has recently been shown to be less successful at controlling viral replication than three drug regimens containing efavirenz after 48 weeks. For this reason, many physicians are following patients on trizivir alone more... Read more »

Trizivir alone or with EFZ?

Dr. Cohen: Since the interim results (March 10) of the AACTG study A5095 on Trizivir vs. Trizivir+EFV as initial treatment for naive subjects indicate even more strongly than earlier studies that the use of Trizivir alone results in virologic...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Thanks for the timely questions, Jim. So here goes... with a big long answer given the "hot topic" nature of your question...As you note - there are new data from an ACTG (US) study which randomized people going on their first regimen to... Read more »

trizivir

Dr. Young,Is trizivir alone enough to start on? Should I be concerned about resistance down the road?Mike...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Trizivir (AZT/3TC/abacavir) is a very convenient triple coformulated drug. The regimen has shown in several studies to be similar in potency to conventional protease inhibitor-based treatments for initial therapy. There has been some concerns... Read more »

Trizivir Opinion

What is your opinion of Trizivir, and would you recommend it as a first defense?...
Judith A. Aberg, M.D.

Response from Judith A. Aberg, M.D.

Washington University, St. Louis School of Medicine
Trizivir (TZV) is a combination of retrovir (AZT,ZDV), epivir (lamivudine,3TC) and ziagen (abacavir, ABC) in one pill taken twice daily. It cannot be used in patients who have severe kidney disease because the amount of 3TC would be too high for... Read more »
Connect With Others

Trizivir

Posted by slitter028, 1 Reply
I have taken Trizivir ever since it came out. The standard dosing is 1 tab bid. My doc has told me on several occasions that i can take both pills at once if it was more convienent for me, because i take viread also, which is once a day, which would... Read more »

Trizivir??????

Posted by Anonymous
I am currently taking epivir, zerit and viracept, but am thinking of switching to Trizivir (epivir,retrovir and ziagen in one tablet). Does anyone have any experience with Trizivir? What kind of side effects? Does it contribute to lypodistrophy less... Read more »

Trizivir resistance

Posted by Anonymous
I was diagnosed in Nov. 2000 and started Trizivir immediatly bc of high VL and low CD4. Immediatly there were reluts and eventually became undetectable and stayed that way for over a year. Now my VL has been increasing but no CD4 decrease. Is... Read more »

trizivir

Posted by Anonymous, 4 Replies
Does anyone else who takes Trizivir have really severe stomach pain?
Also, I am batteling with Lymphoma. Read more »