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Telzir

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Fosamprenavir (Telzir, Lexiva)

What Is Fosamprenavir? Fosamprenavir is a drug used for antiretroviral therapy (ART). It is also called Lexiva TM . In some countries, it is called Telzir. It is manufactured by ViiV Healthcare. Fosamprenavir is a pro-drug. The drug you swallow is not active against HIV. It breaks down in the body to produce the active form, which is the drug amprenavir (see Fact Sheet 445 ). Fosamprenavir is a protease inhibitor. These drugs prevent the...
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Viread/Emtriva/Norvir/Telzir as first line treatment?

Hello, a friend of mine with a VL of about 400,000 and about 200 CD4s was suggested the following first line treatment: Tenofovir, Emtricitabin, Ritonavir and Fosamprenavir. I wonder whether this makes sense since the gold standard is...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
on boosted PIs instead of NNRTIs-- this is generally because the newest PIs, atazanavir (Reyataz) and fosamprenavir (Lexiva, Telzir) are much easier to take (fewer pills, less side effects and no diet restriction for fosamprenavir) yet still have... Read more »

Switching to Lexiva/Telzir, Norvir and Truvada

lipid levels and without the "nasty" AZT part of combivir.He suggested to switch to an even better combination: Lexiva/Telzir, Norvir and Truvada, that can also be taken once daily like Reyataz.But now I've read that only...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post and kind words.With the arrivals of atazanavir (Reyataz) and fosamprenavir (Lexiva, Telzir), we're seeing a resurgence in the use of first-line protease inhibitors.The proposed regimen of fosamprenavir/ritonavir... Read more »

muscle and bone pain

dear doctor,thank you for answering this question. I am on treatment: morning telzir/norvir, emtriva and viread. Evening: telzir/norvir. Also I take coversyl for my blood pressure. But since 6 months I have terrible...pains so much I have problems...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
You need to have a through clinical evaluation to assess more precisely whether bones, muscles, or joints are the site of the pain. Labs and sometime X-ray evaluation may also be needed. Fosamprenavir rarely causes bone/muscle pain (also true of the... Read more »

Changeover to Etravirine

Hi, I am about to change my regime from Truvada and Telzir to Truvada and Intelence. I was told that I can do a straight switch, but I note from the information on Intelence that the Telzir/fosamprenavir...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Though there is concern about somewhat unpredictable interactions between fosamprenavir and etravirine when used together. For a simple switch from one to another I would be less concerned (I would be concerned if your viral load is not undetectable... Read more »