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Saquinavir And Aids

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Get the Facts
AIDSinfo

An Overview of Invirase (Saquinavir mesylate)

... sack-KWIN-uh-vihr MEH-sih-LATE --> Brand Name: Invirase Other Name(s): Ro 31-8959/003 (Saquinavir mesylate), SQV, Saquinavir mesylate, Saquinavir monomethanesulfonate (Saquinavir mesylate) Drug Class: Protease Inhibitors Saquinavir mesylate, also known as Invirase, and saquinavir, formerly marketed in the United States
Ask the Experts

can you get hiv/aids if you.. (QTND: HIV TRANSMISSION BETWEEN TWO HIV NEGATIVES, 2008)

me and my partner have been curious about trying anal sex. we are both hiv/aids free and free of any other std's. we were curious, can we get aids from anal sex even if you both are disease free?
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...attack the HIV enzyme protease and include amprenavir, atazanavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, tipranavir, and darunavir. Fusion inhibitors stop virus from entering cells. To date, only one fusion... Read more »

Questions on retroviral enzyme inhibitors in HIV treatment

I wonder if you could tell me some information regarding the absorption and excretion metabolism of saquinavir and zidovudine in HIV/AIDS treatment ?
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...last long enough with standard dosing so that you can take either of these just every 12 hours. Now, unlike with zidovudine, saquinavir can be further "boosted" by ritonavir - and studies show that not only can we dose this med twice a day, we... Read more »

Viracept/Saquinivir ALWAYS better than justViracept?

Dr. Gallant: In a couple of your answers you've said that Viracept (as well as Ritonivir) greatly strengthens the otherwiseweak Saquinivir against HIV in combo therapy with nukes. My boyfriend just got d4T/3TC +Viracept prescribed to him ashis...
Joel Gallant, M.D.

Response from Joel Gallant, M.D.

Johns Hopkins University, School of Medicine
...Nelfinavir (Viracept) does not "greatly strengthen" saquinavir (the way ritonavir does), but it does modestly enhance saquinavir levels. While with ritonavir you can take reduced doses of Read more »

garlic

am 62kg & on ARVs can i use garlic
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...your blood, making them less effective. The dose of garlic that was shown to significantly lower blood levels of Fortovase (saquinavir) was four grams of raw garlic. That's also enough to keep all vampires out of Transylvania for a fortnight! In... Read more »
Articles
The Body PRO

Ritonavir-Saquinavir Combination Therapy in Patients with Advanced HIV Infection

...Conference onRetroviruses and OpportunisticInfections in Washington,D.C. examined the effect of the combination ofritonavirand saquinavir in advanced HIV positive patients. Prior to these studies,the combination of ritonavir and saquinavir had... Read more »
AIDS InfoNet

Saquinavir (Invirase)

... What Is Saquinavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Read more »
Insight Medical Communications Inc.

Use of Pharmacokinetic Enhancement in Antiretroviral Treatment-Experienced HIV Patients

...extensive first-pass metabolism by CYP450 reduces oral bioavailability of PIs to varying degrees. For example the bioavailability of saquinavir is 60%. 14 , 15 As with P-glycoprotein, the situation is complicated by the fact that PIs are... Read more »
AIDS InfoNet

Drug Names and Manufacturers

..."/r" after the name of a protease inhibitor, that means it is boosted with a small dose of ritonavir. For example, SQV/r means saquinavir boosted with ritonavir. At present, only lopinavir and ritonavir are available in a single pill. Year... Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
...I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law Read more »

hic

Posted by Anonymous
...-------------------------------------------------------------------------------- Indinavir (Crixivan) Nelfinavir (Viracept) Ritonavir (Norvir) Saquinavir (Fortovase) Stavudine plus lamivudine Efavirenz (Sustiva) Nevirapine (Viramune) ... Read more »

World AIDS Day 2006: raising 'HIV/AIDS' Awareness

Posted by Anonymous
...World AIDS Day 2006: Raising 'HIV/AIDS' Awareness We urgently need to raise 'HIV/AIDS' Awareness to stop the epidemic spread of AIDS-related Myths, HIV-related Read more »