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Raltegravir Facts

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AIDS InfoNet

Raltegravir (Isentress)

What Is Raltegravir? Who Should Take It? What About Drug Resistance? How Is Raltegravir Taken? What Are the Side Effects? How Does it React With Other Drugs? The Bottom Line What Is Raltegravir? Raltegravir (Isentress) is a drug used for antiviral therapy against HIV. It was formerly known as MK-0518. It is manufactured by Merck. Raltegravir is the first "integrase inhibitor" drug. When HIV infects a cell, it...
Ask the Experts

new hiv med Raltegravir looks good and is the future of hiv meds

Dr Bob, l read there is a new hiv drug on the market which is early in its stage called raltegravir and its a integrase inhibitor, a nother name for it could be isentress, the drug has no reported side effects... Dr Bob what do you know about this...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,What do I know about Isentress (raltegravir)?? Well, I know it quite well. In fact, I just swallowed one!Isentress is indeed an inhibitor of the HIV-1 integrase enzyme. This is a novel new mechanism of action for antiretroviral agents. It is... Read more »

Considering Raltegravir Trial

Hi from the UK.I am a 41yo male about to start meds for the first time. My resistance tests are all good (no resistance showing) so I have a wide choice of meds to choose from.My question is: My HIV doctor invited me to take part to a study to...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello G. and thanks for your post.I appreciate your interest in participating in clinical trials- we all are indebted to the many thousands or participants before you.As for the study that you're interested in- know that with all studies, there is... Read more »

Raltegravir & Side Effects

Hi from the UK.I know that this forum is for Safe Sex and HIV Prevention but I would like to ask you this question since I know that you have personally battled with lipodystrophy and also you mentioned already that you are taking Raltegravir.I am a...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello G,1.Isentress (raltegravir) plus Truvada is not associated with a significantly increased risk of lipoatrophy or lipodystrophy. (Thymidine analogs, such as D4T and AZT, are linked to lipoatrophy and some protease inhibitors have been... Read more »

Mental-health effects of Truvada/Isentress combination?

For about four months, I've been taking a Truvada-Isentress combination - my first medication after seven years HIV+. My doctor warned me there have been no long-term studies on Isentress' effects, but I agreed to try it anyway. I seem to be...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There have been a few causes of depression seemingly triggered after starting raltegravir (4 cases reported from Vancouver, BC in the journal AIDS-see below for the authors comments on those cases).epression and other psychiatric adverse events in... Read more »
Articles
AIDS InfoNet

Drug Names and Manufacturers

Reverse Transcriptase Inhibitors ("Nukes") Non-Nucleoside Reverse Transcriptase Inhibitors Protease Inhibitors Integrase Inhibitors Attachment and Fusion Inhibitors Antisense Drugs Immune Modulators None of these drugs can... Read more »
AIDSinfo

An Overview of Isentress (Raltegravir, MK-0518)

ral-TEG-ra-vir --> Brand Name: Isentress Other Name(s): MK-0518, MK0158, RAL Drug Class: Integrase Inhibitors Raltegravir, also known as Isentress and MK-0518, is a type of medicine called an integrase inhibitor. Integrase... Read more »
Test Positive Aware Network

Isentress

Common Name: raltegravir (formerly MK-0518) Brand Name: Isentress Class: HIV integrase inhibitor (also called integrase strand transfer inhibitor or INSTI) Standard dose: One 400 mg film-coated tablet twice a day. Can be taken... Read more »
AIDS InfoNet

U.S. Antiretroviral Therapy Guidelines

Why Do the Guidelines Keep Changing? Viral Load and CD4 Cell Testing Resistance Testing When to Start Treatment Goals of Therapy What Drugs Should Be Used First? Interrupting Treatment When to Change What to Change To? Why... Read more »
Connect With Others

Those taking, Raltegravir, Truvada & Atazanavir

Posted by sweetvanilla27, 1 Reply
I am wanting to hear from anyone who have experienced taking Raltegravir, Truvada & Atazanavir and how you have got on with the meds? I first started taking meds in May this year I was put on Truvda and Sustiva first, and was taken off them due... Read more »

raltegravir questions please help me out here

Posted by themushroom, 2 Replies
I am currently infected with a virus in the HIV family It is called Xenotropic murine leukemia virus related virus (XMRV) and is responsible for my HIV like illness and symptoms (chronic oral thrush shingles ect) It is a retro virus that... Read more »

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies
In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »