Prezista Dosing

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Articles

FDA Approves Once-Daily Prezista Dosing for Treatment-Experienced Adults

On December 13, 2010, FDA approved new labeling for Prezista (darunavir) to include a once daily dosing for treatment-experienced adult patients with no darunavir resistance associated substitutions. The major revisions to the package insert are... Read more »

New 75 mg Prezista Tablet and Corresponding Pediatric Dosing Information Approved

On December 18, 2008 FDA approved new pediatric dosing recommendations for a new 75 mg Prezista (darunavir) tablet formulation for patients from 6 to less than 18 years of age. Section 1 Indications and Usage, Section 2 Dosage and Administration,... Read more »

For Some, Taking Prezista Once a Day Is Enough

In 2010, the FDA approved a change in the dosing for Prezista (darunavir) for people who have been on HIV treatment before. This could possibly help people take their regimens on schedule every day. However, the dosing change should not be attempted... Read more »

Ask the Experts

missed prezista/norvir dose

Hi Drs,I am on Truvada+Prezista/Norvir since 5 months ago and currently (June) vl is undetectable and CD4 288 (after being up to 332 after just 2 months on meds??). However yesterday I took my Truvada dose just after waking up, but forgot to take...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello and thanks for your post.Adherence is a very important aspect to the success of treatment. We typically strive to achieve 95% adherence. If you've only missed one dose in 5 months (or 1 in ~150), your adherence level is... Read more »

Prezista Underdosing

Hi I recently seroconverted, and my doctor prescribed for me Prezista 300mg BID instead of 600mg BID. I took this for almost a month until I realized what had happened. What sorts of problems can this lead to? ...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post.I hope that your doctor prescribed ritonavir (Norvir) with your darunavir (Prezista). Your dosing is clearly under the recommended level- fortunately it might not be as bad as it could be. There is substantial evidence that... Read more »

Is my treatment working? Prezista+Truvada+Norvir

Hi, I recently started taking HIV medicines, May 22nd of this year to be exact. When I started medicine, my VL was about 2,500. My CD4 was about 350. The resistance profile done showed NO resistance to any of the HIV medicines. 2 weeks after...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

Dear worried fellow- NYer,Your response is not out of line from what can be expected. Your initial response has been quite good. Most people have achieved an undetectable viral load by 4 to 6 months. It may take longer for those people starting... Read more »

Prezista stoped making the 600mg?

Why did the company who makes Prezista stop making the q.d. dosage of 600mg?I have been taking that dose for over a year now.Recently my pharmaist told me that the company stopped making that dose.The pharmaist had to call my phsyican to change the...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

I am not aware of that. Prezista comes in 300, 400, and 600mg tablets. Current dosing is 800mg once daily: (2)400mg tabs plus 100mg ritonavir once daily; or 600mg twice daily: (1)600mg or (2)300mg tabs plus 100mg of ritonavir twice daily.... Read more »

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Prezista + Norvir + Truvada

Posted by notreadyforthis, 1 Reply

So I took my first dose of meds last night. My doctor started me on this combo:

Prezista (darunavir), two 300mg tabs, plus
Norvir (ritonavir), one 100mg soft gelcap, plus
Truvada (emtricitabine+tenofavir) one 200mg/300mg respectively.

I take this combo... Read more »

Prezista - New PI designed for Resistant Virus

Posted by Survivor, 2 Replies

WASHINGTON, June 23 (Reuters) - U.S. health officials on Friday approved the use of a new HIV drug, made by Johnson & Johnson <JNJ.N>, in combination with related therapies to help treat patients who do not first improve with other... Read more »

Splitting Prezista 600mg into thirds...

Posted by lovelife, 2 Replies

I need to take Prezista 800mg. If I have only Prezista 600mg, can I brake the pill into thirds so I can take one 600mg and then add 200mg more from the splitting?
Is this feasible? Safe? Read more »

Itchy bumps on face--On Isentress,Prezista,Norvir

Posted by llee, 2 Replies

Hi all,

my doctor put me on a combo of Isentress,Prezista,Norvir in June. Soon after I started I got itchy bumps all over my face, and also on my neck and upper chest and upper arms. According to the doctor it's because of Immune Reconstitution... Read more »

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