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Pregnancy And Antiretroviral Pharmacokinetics

Here's a taste of what has to offer on this topic:
HIV i-Base

Tenofovir Population Pharmacokinetics in Pregnancy

Changes in tenofovir pharmacokinetics (PK) during pregnancy are associated with weight gain and reduction in serum creatinine with enhanced glomerular filtration, according to an analysis presented at the 14th International Pharmacology Workshop. ... Read more »
HIV i-Base

Washout Pharmacokinetics of Transplacental Raltegravir in Neonates

There are limited data to guide dosing of antiretrovirals in neonates (and limited approved drugs for this age group). There is an urgent need for new options both for prophylaxis for neonates at high risk of infection and to treat vertically... Read more »
Merck & Co., Inc.

Important Drug Warning: Results of Pharmacokinetic Study in Healthy Volunteers Given Victrelis (Boceprevir) and Ritonavir-Boosted HIV Protease Inhibitors May Indicate Clinically Significant Drug Interactions for Patients Coinfected With Chronic Hepatitis C and HIV

Dear Health Care Professional, The purpose of this communication is to inform you of recent pharmacokinetic study results evaluating drug interactions between VICTRELIS, an oral chronic hepatitis C virus (HCV) NS3/4A protease inhibitor, and... Read more »
Ask the Experts

pregnancy and antiretroviral medication

hi..can u pls tell me the medication after getting rape that is antiretroviral medication would ever tamper in becoming pregnant in ur life? wat r the long term side effects of that drug?...
Sharon Lee, M.D.

Response from Sharon Lee, M.D.

University of Kansas Medical Center
There are several antiretroviral regimens used as prophylactic medicine after a rape to try to prevent HIV infection. Some of the medicines may cause a problem if pregnancy occurs while the woman is taking the medicine. However, there are no known... Read more »

Iniitating antiretrovirals in pregnancy

I am a Clinical Immunologist seeking your opinion for the initiation of antiretroviral therapy for a gynecologist who tested HIV positive during the first trimester of pregnancy. Most probably, she aquired the infection occupationally as her...
Katherine Luzuriaga, M.D.

Response from Katherine Luzuriaga, M.D.

University of Massachusetts, Medical School
In settings where combination therapy is possible, a combination of ZDV chemoprophylaxis with additional antiretroviral medications to optimize maternal health is recommended for infected women whose clinical, immunologic, or virologic status... Read more »

Pregnancy, Kaletra and Lexiva

Hi Experts,My girlfriend and I are planning to have a baby.We are both Poz (she is 40 and I am 42yrs). I am not on medications (my vl is around 1400 and Cd4 around 560). She is currently on Sustiva and Truvada.We realized that sustiva is not...
Katherine Luzuriaga, M.D.

Response from Katherine Luzuriaga, M.D.

University of Massachusetts, Medical School
Efavirenz (Sustiva) is not recommended for use during pregnancy because of birth defects observed in baby monkeys whose mothers received the drug during pregnancy. Similar birth defects have also been noted in some human babies whose mothers took... Read more »


I am an HIV Positive Female my Husband is Negative, i am on medication since last two years my regime are ( Nevrapine, zidovidine, lamividine)planning for a baby what can be a safe methods, so can be a pregnant and my Husband will remain HIV...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,Yes, it is certainly possible to have a safe pregnancy. There are really two issues to consider:1. Not putting your husband at risk for HIV. This is best accomplished by artificial insemination. (See below.)2. Preventing mother-to-child HIV... Read more »
Connect With Others

HIV drugs and pregnancy

Posted by Anonymous
Hi there,
I've been reading through the posts and hope that I am not intruding with my post here. I am doing research for a film on antiretroviral drug treatments for HIV pregnant women and for children. When I started I thought that the options... Read more »

"Positive living" eclipsed by ARV (Antiretroviral

Posted by bradford, 1 Reply
"Positive living" eclipsed by ARV (Antiretroviral) drive

Originally, it seemingly appeared that anyone infected with HIV would progress to disease and die. This has long since been realized to no longer be true. We have individuals all over the... Read more »

AIDS & Pregnancy

Posted by Anonymous, 1 Reply
would hiv show up after 2 years or is that too they test during pregnancy?

Read more »

Pregnancy & HIV Tests

Posted by Anonymous, 1 Reply
I've heard that pregnancy can cause a false positive HIV result. Is that true? I'm pregnant, and i was tested a little over 3 months since my last unprotected sexual encounter. The result was negative. Should I test again or is 3 months good... Read more »