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PI Facts

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Test Positive Aware Network


Common Name: lopinavir/ritonavir Brand Name: Kaletra Class: HIV protease inhibitor (PI) Standard dose: Two 200/50 mg tablets twice a day or four 200/50 mg tablets once daily for first-time therapy (no once-daily dose if taken with Sustiva or Viramune). Three tablets twice a day may be considered for treatment-experienced people or those taking it with Sustiva or Viramune. Half-strength film-coated tablet available. Tablets...
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Genotype and Phenotype Results

Hello doctor:I was on Viracept, AZT and Epivir for over 2.5 years and have been HIV+ for about the same.. My viral load went up for several visits so I took the above listed tests. My first question is, why does the genotype list Viracept as a...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
First - regarding what appears to be a conflict between the genotype and phenotype test. If the bar graph of the phenotype test shows that you are not sensitive to viracept and yet the Genotype shows no resitance to viracept, I would guess that the... Read more »


You keep referring to this large study comparing hiv+ to hiv-and how there is no difference in weight gain between the two groups. Please tell me the name of this study so i can research it myself. did the study research fat redistribution or just...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
The study I was referrring to is the FRAM study which published initial finding recently in the Journal of AIDS (JAIDS). As I also discussed, lipid levels clearly increase in many but not all patients on certain drugs such as Kaletra. There are wide... Read more »

What to do about my meds!

Hello. I'm not very happy with my current medication combo. I'm a 22 year old gay male and HIV infected. I've been on many of the medications and off due to side effects... My current regimen is Reyataz, Epivir, & Zerit. Previous to that I was...
Sharon Lee, M.D.

Response from Sharon Lee, M.D.

University of Kansas Medical Center
You certainly have good reason for frustration with all you've been through. The trade-off with the medicines is longer life. Clearly, you are the only one who can really determine if the cost (side-effects) is worth it to you. You have a few... Read more »

Cholesterol and PI's

My partner was diagnosed in July of '99 with HIV. At that time his CD4=48 & VL>500,000, & had PCP. Everything is fine now, VL=undetectable, CD4=500+. He takes crixivan & combivir, never misses a dose, and his numbers continue to improve. He has...
Judith A. Aberg, M.D.

Response from Judith A. Aberg, M.D.

Washington University, St. Louis School of Medicine
I cannot second guess the opinion of your partner's physician regarding cholesterol screening. From my perspective, all patients should be pre-screened for hyperlipidemia (high lipid levels) by checking a fasting lipid panel prior to starting... Read more »
Test Positive Aware Network


Common Name: etravirine Brand Name: Intelence Class: non-nucleoside analogs (also called non-nucleoside reverse transcriptase inhibitors, NNRTIs or non-nukes) Standard dose: Two 100 mg tablets twice daily, with food. Take missed... Read more »
The Well Project


Table of Contents What Is PK? How Is PK Studied? Drug Interactions and Drug Boosting Do Men and Women Process Drugs Differently? Pharmacokinetic Testing How to Make PK Work for You References What Is PK? ... Read more »
The Well Project

Diabetes and HIV/AIDS

Table of Contents What Is Diabetes? Symptoms of Diabetes Glucose Tests Who Is at Risk for Diabetes? What Problems Can Diabetes Cause? How Are Diabetes and Pre-Diabetes Treated? HIV and Diabetes Taking Care of Yourself ... Read more »
The Well Project

Side Effects of HIV Drugs

Table of Contents Side Effects and HIV Drugs Being Informed About Side Effects Helps Women and Side Effects Taking Care of Yourself Side Effects and HIV Drugs Over the years, drugs have been developed that can treat a wide... Read more »
Connect With Others

PI Monotherapy advice

Posted by logopolis, 2 Replies
Admin OptionsEdit Discussion Close Discussion Edit Your Tags Cancel Delete Discussion Hi, My partner has been asked to take part in a clinical trial - Protease Inhibitor monotherapy versus Triple Therapy. Just gathering some info before he... Read more »


Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

What to do.......?

Posted by Anonymous, 5 Replies
Hi. I have just been diagnosed this week with poor labs - cd4 count - 57, viral load 800,000+. I will commence with Truvada+Sustiva and switch to Atripla as soon as it is approved in England. My question is this - has anyone else been in situation?... Read more »

advice please

Posted by Anonymous, 1 Reply
I am a female that has currently switched from Viracept to Sustiva because of the beginning symptoms of lipodystrophy and have now put in an order for Serostim to attempt to combat this. My question is dosage. My doctor suggested starting at 3mg... Read more »