Nelfinavir Side Effects

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Nelfinavir (Viracept)

What Is Nelfinavir? Nelfinavir, also called Viracept, is a drug used as part of antiretroviral therapy (ART). It is manufactured by ViiV Healthcare. Nelfinavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV into specific pieces needed to build a new virus. Protease inhibitors "gum up" these scissors. Nelfinavir also fights some types of...

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Nelfinavir -v- Nelfinavir/Saquinavir Combo

I have been on AZT, 3TC and Crixivan since last December and my VL has dropped to (last reading) 175. However, I amseriously considering a switch from Crixivan to Nelfinavir (Viracept) because ofthe friendlier dosing schedule, and removalof the risk...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

There may be a benefit to using saquinavir in addition to nelfinavir, but we really don't know yet. Nelfinavir doesn't increase saquinavir levels as much asritonavir does. In the only studies being done on this combination, they're... Read more »

About Viracept(Nelfinavir).

Can you please introduce the new protease inhibitor Viracept(Nelfinavir)? I would like to know moreabout it. What is the dosage? What are some of its side effects? How does it affect CD4 cell count andviral load?...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Nelfinavir (Viracept) is the fourth protease inhibitor to be approved by the FDA. The dose is 750 mg (three 250 mg capsules) three times daily. It should be taken with food, and does not have to be taken exactly every 8 hours. The most common... Read more »

Nelfinavir

Dear Dr.I read on this Forum and in the new Medscape guidelines that Nelfinavir can now be used 5 cap every 12 hours. Is this safe considering the half-life of this medication is 3.5 - 5 hours? Isn't there a higher risk for developing...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

The potency appears to be the same when the twice versus three times a day regimens were compared. Side effects were no different. Sorry you got me. What is Biovir? I would simplify your life and switch to the twice a day regimen and take it with... Read more »

Now that Nelfinavir is Available..

I have been taking 3TC, D4T (both 11 months) & Norvir/Ritonavir now for 7 monthsresulting inundetectable viral load and 400 CD4s. I tried Crivixan and got kidney stones. I currently still get boutsof diarrhea, nausea and constant fatigue. Both...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

If your viral load is undetectable and you decide to switch your protease inhibitor, then you don't need to switch your other drugs. That rule only applies when the regimen is failing (in other words, when you have detectable virus).You will... Read more »

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Viracept/Epivir/Videx side effects

Posted by TimInAtlanta, 3 Replies

I started the viracept/videx/epivir combo about 2 months ago. Has anyone had any side effects related to memory / thinking / vision with it?

Thanks.

Tim

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does anyone else have a trouble with Viracept

Posted by Anonymous, 2 Replies

I'm 25 I have been living with HIV since June 5th 2001. I've been taking Trizivir and Viracept for the past 4 months. The side effects have been a major pain I just hope this isn't a sign of things to come!!

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viracept

Posted by Anonymous, 1 Reply

can anyone share any longer term side effects of treatment with viracept(more than 2 years)I went through some very slight initial diareaha(extremely mild and resolved quickly)But lipo is setting in(pyshical as well as lipids)but I've lost 70% of... Read more »

Trizivir??????

Posted by Anonymous

I am currently taking epivir, zerit and viracept, but am thinking of switching to Trizivir (epivir,retrovir and ziagen in one tablet). Does anyone have any experience with Trizivir? What kind of side effects? Does it contribute to lypodistrophy less... Read more »

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