NRTIs And Hiv

Here's a taste of what TheBody.com has to offer on this topic:

Articles

Know Your HIV Drugs: NRTIs (The Nukes)

In recent years the drug choices available to people with HIV have increased substantially. There are currently 16 approved antiviral drugs for HIV and these drugs are usually used in combinations of three or more to create an effective antiviral... Read more »

HIV Drugs and the HIV Lifecycle

Table of Contents The Basics The HIV Lifecycle Approved HIV Drugs Combining HIV Drugs The Bottom Line The Basics HIV drugs cannot cure HIV but they can help you stay healthy by preventingthe virus from reproducing (making copies... Read more »

HIV JournalView: Top 10 HIV Medical Stories of 2006

Table of Contents Introduction Top 10 Medical Stories of 2006: The SMART Study -- A Treatment Interruption Trial CD4+ count-guided interruption of antiretroviral treatment By the Strategies for Management of Antiretroviral Therapy (SMART)... Read more »

Ask the Experts

Resitant to all PIs & almost all NRTIs

Hello,I have been HIV+ for 25 years and have done pretty well on my HIV therapies which I began about 17 years ago. Last year my viral load began to increase so my doctor & I decided to switch my regimen. My Pheno & Genotype test showed me...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

You have done well to tell me a great deal about your situation, but I will caution you and other readers of this website that complex cases with high levels of resistance and a long treatment history are the most difficult to summarize accurately,... Read more »

Off label use of NRTIs for obesity

Hi there doctor,Thanks for this fantastic web site and the work you do.Out of curosity, with the focus on NRTIs, esp. the D-drugs and azt on fat loss, has there been any discussion of using this category of drugs off-label to treat obese or...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

NRTIs are generally expensive with a wide range of potential mild or serious side effects. The effect on fat resulting in fat loss is believed to be due partly to fat cell death possibly linked to mitochondrial toxicity which has potentially serious... Read more »

Sustiva causing resistance to other nNRTIs

Sustiva (efavirenz)-Induced Mutation in Subtype C HIV May Confer Multi-NNRTI ResistanceA mutation at codon 106 in HIV-1 clade C viruses that occurs after exposure to efavirenz appears to result in high-level resistance to other non-nucleotide...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for pointing out the research.So far, this does not seem like a very common issue-- however, a different mutation at codon 103 is commonly found among persons with clade B HIV (the US, Western Europe flavor)- this mutation usually causes high... Read more »

Dr. Cohen, how does treatment for HIV2 differ from HIV1?

Dr. Cohen: Hello. Thanks for your very complete answers concerning HIV and its treatment. My question relates to the differences between treatments for HIV1 and HIV2. I have heard that some classes drugs effective as part of HAART are ineffective...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

Only the nonnucleoside class is not expected to work against HIV 2 - the nucleosides (azt etc) including tenofovir should work fine, and the protease inhibitors do as well. So there are many three drug HAART combos that would work against HIV2 -... Read more »

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Connect With Others

Drug Resistant HIV

Posted by Anonymous

Hi

I just found out the strain of hiv i have is resistant to possibly a whole class of NRTIs and PIs..any experience with this for any of you? what could the options be for someone in my situation? I am still treatment naive.

Read more »

want to have a baby, but worried

Posted by kolo, 1 Reply

quote: Adam Legge, Monday, April 16, 2007
Antiretroviral drugs used to prevent HIV transmission from mother to child can cause genetic damage in infants that may increase their risk of developing cancer in the future, according to new research.

The... Read more »

info

Posted by Anonymous, 1 Reply

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Failed a Urinalysis

Posted by SDNavy, 4 Replies

Hey,

I recently had a random urinalysis at work, and come to find out I failed it. I do not do illegal drugs, but I do take the meds my doctor have prescribed to me. I am getting mixed answers from various doctors as to wether or not my meds can make... Read more »

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