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NNRTI Dose

Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
The Well Project

HIV Drug Chart/Overview

Table of Contents Introduction Nucleoside and Nucleotide Reverse Transcriptase Inhibitors (NRTIs) Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) Integrase Inhibitors Protease Inhibitors (PIs) Entry Inhibitors Combination Pills Introduction The number of drugs available to fight HIV keeps growing. This is good news,but...
Ask the Experts

protecting the nnrti's

If the nnrti's are so important and cross resistance a big problem, can't we use a second nnrti to protect the first.Would using two nrti's and two nnrti's together be any good.Also if the four drug regimen were too toxic could the second nnrti be...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
This is a great and well formulated question.Turns out that the mechanism of action of the NNRTIs makes it unlikely that two will work better than one, since the two drugs would compete for the same binding site in the viral reverse... Read more »

HIV2 INFECTION AND TREATMENT

CAN I USE 3 NRTI DRUGS SUCH AS AZT/d4T/ddI,IN COMBINATION AS THE NNRTI DRUGS ARE INEFFECTIVE IN NORMAL DOSES, WHERE AS PI DRUGS WITH THE EXCEPTION OF NELFINAVIR,&SAQUINAVIR,THE OTHER PI DRUGS ARE RELATIVELY IN EFFECTIVE AND ALSO BECAUSE AND THE...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is fairly little data on the use of AZT/D4T /ddI together and my guess would be that the effectiveness would be modest/limited with a fairly high rate of side effects (AZT and D4T are both thymidine analogues and generally should not be used... Read more »

Med change from NNRTI to PI?

My husband has a very low cd count of 8 and also hep C and hep b, along with depression which is causing adherence problems, currently on combivir and sustiva, twice daily, he's missed doses quite a few times. How long does it take to develop...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Viral resistance may develop quickly with a NNRTI-based regimen when adherence is spotty. On this basis alone a once daily PI-based regimen might make more sense for your husband. An example would be Truvada, Norvir, and Reyataz. It bears... Read more »

Part 2 - Is NNRTI class a MUST?

Thanks Dr. Wohl,I'm currently taking 1)Sustiva 300mg twice daily 2)Kivexa once daily 3)Kaletra "tablets" (no fridge) 2 Bid and I WANT to drop 1)Sustiva (due to an episode of "almost hurt someone")....and keeping only Kivexa + Kaletra, possible?For...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
I think you can drop the Sustiva IF it is likely your virus is not resistant to the abacavir in Kivexa (also called Epzicom) or the Kaletra. Note, if you drop the Sustiva (after discussing this with your doctor), the dose of Kaletra will need to be... Read more »
Articles
The Body PRO

Addition of Short-Course Zidovudine/Lamivudine to Single-Dose Viramune Decreases Development of Maternal NNRTI-Resistant HIV

The crucial issue of mother-to-child transmission (MTCT) of HIV in underdeveloped countries was again raised at this conference, with more data reported on nevirapine (NVP, Viramune) resistance. Reducing transmission by 50% with only 2 doses per... Read more »
Test Positive Aware Network

Atripla

Combo Drug Common Name: efavirenz, emtricitabine, and tenofovir disoproxil Brand Name: Atripla Class: Dual-class fixed dose combination; single dose regimen -- nucleoside analogs (also called nucleoside reverse transcriptase... Read more »
Test Positive Aware Network

Intelence

Common Name: etravirine Brand Name: Intelence Class: non-nucleoside analogs (also called non-nucleoside reverse transcriptase inhibitors, NNRTIs or non-nukes) Standard dose: Two 100 mg tablets twice daily, with food. Take missed... Read more »
AIDS InfoNet

Nevirapine (Viramune)

What Is Nevirapine? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Nevirapine? Nevirapine is a drug used as part of antiretroviral therapy... Read more »
Connect With Others

Excessive Mastubation

Posted by Anonymous, 5 Replies
Ever since I found out that I'm poz, I've been spending a lot more time mastubating. Is that normal? Or could it be because of the amount of time I've been spending reading posts about sexual issues? Pleasing myself has become an every day thing... Read more »

Two weeks down and a life time to live

Posted by trulife, 2 Replies
Well folks...it's the end of two weeks on Atripla and so far things are going well. Side effects have been limited and are now subsiding. My biggest problem so far is swallowing the pill. I have always had trouble swallowing pills...go figure...a... Read more »

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

Skipping Doses

Posted by chrisnxs, 2 Replies
Hello Everyone, can someone please elaborate on the severity of skipping meds? My bf is positive and has been on meds for about a year. He's on my insurance and it kills the price down to a point where he can get his meds pretty easily. I discovered... Read more »