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Get the Facts
AIDS InfoNet

Maraviroc (Selzentry, Celsentri)

... What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US... and Celsentri elsewhere) was formerly known as UK 427,857. It is a drug used for antiretroviral therapy. It is manufactured by ViiV Healthcare. Maraviroc is the first "attachment inhibitor"...
Ask the Experts

Atripla and Maraviroc

...soon (my CD4's range between the 400 and 450, CD4/CD8% is 23, VL 16.000).My doc suggested to start with Atripla AND temporarly Maraviroc. He calls it a 'mini trial' as he is curious to see how fast I would become undetectable. After that is...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...from a year ago may not accurately reflect the current population of virus in your blood since your virus may evolve to bypass maraviroc by using another receptor. This change can happen even if you are not taking meds. Also, the test to detect... Read more »


...My viral load has become detectable and my doctor would like to put me on Maraviroc and Isentress. I have been reviewing both of these drugs and I have some concerns with Maraviroc. I know it works on the CCR5
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...(or co-) receptor for HIV to enter the T cell. HIV may also use another co-receptor (called CXCR4) to enter the cell. Since maraviroc only blocks virus that use CCR5, it is important to know what type of virus you have before you would use this... Read more »


...for cd4 and viral load will be out and i will see an hiv specialist for the drug regimen.i read about new ccr5 inhibitors like maraviroc and it sounds great.i learnt that it stops virus from entering the cells .doctor, can maraviroc or anyother...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...There is comparativey little info about use of CCR5 inhibitors like maraviroc for initial treatment of HIV infection. Since the success rates for initial therapy with current often simple (once daily ) Read more »

Maraviroc, Isentress & Atripla?

...- but I am sensitive to all other classes. I also am CCR5- tropic. I have never taken a PI; or NNRTI. My doctor suggests Maraviroc; Istentress & Atripla. He is adding Atripla to keep a particular mutation he said I have, that is 'good.' I am...
Edwin DeJesus, M.D., F.A.C.P.

Response from Edwin DeJesus, M.D., F.A.C.P.

...on what your regimen should be, but perhaps using a PI and an NNRTI, with a consideration of adding a 3rd drug (Isentress or Maraviroc, or even a nucleosideon some circumstances) may be quite enough. Although all those new drugs have been... Read more »

An Overview of Selzentry (Maraviroc, Celsentri)

... Brand Name: Selzentry Other Name(s): Celsentri, MVC, UK-427,857 Drug Class: Entry and Fusion Inhibitors Maraviroc, also known as Selzentry, is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking HIV... Read more »
InfoRed SIDA

Maraviroc (Selzentry, Celsentri)

... ¿Qué Es Maraviroc? ¿Quién Debe Tomar Maraviroc? ¿Qué Es la Resistencia a los Medicamentos? ¿Cómo se Toma Maraviroc? ¿Cuáles... Son los Efectos Secundarios? ¿Cómo Reacciona Maraviroc con Otros Medicamentos? En... Read more »
British Columbia Centre for Excellence in HIV/AIDS

Genetic Test Predicts Response to Maraviroc in Treatment-Experienced HIV Patients

...determining HIV tropism can be used to effectively identify patients who will respond to treatment with the CCR5 antagonist maraviroc, according to new data presented today at the 5th International AIDS Society (IAS) Conference on HIV... Read more »
U.S. Food and Drug Administration

Traditional Approval and Label Changes for Selzentry (Maraviroc)

... On November 25, 2008, FDA granted full, traditional approval for the use of maraviroc in treatment-experienced patients infected with CCR5-tropic HIV-1. The change from accelerated to traditional approval was based...genotypic and phenotypic... Read more »
Connect With Others

chicago,il. Alguien sabe de alguna cura para vih?

Posted by adriana, 3 Replies
hola, mi nombre es adriana y auque tengo viviendo con el virus 4 anios en realidad no tengo mucha informacion creo q por no querer pensar demaciado en este virus lo hice a un lado, claro sin dejar de cuidarme. me gustaria saber si alguien de ustedes... Read more »

Entry Inhibitors

Posted by Anonymous, 1 Reply
Does anyone know anything about the new entry inhibitors? I think Pfizer and Schering both have drugs in development. Should we be hopeful? Read more »