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Maraviroc Facts

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AIDS InfoNet

Maraviroc (Selzentry, Celsentri)

What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US and Celsentri elsewhere) was formerly known as UK 427,857. It is a drug used for antiretroviral therapy. It is manufactured by ViiV Healthcare. Maraviroc is the first "attachment inhibitor" drug. When HIV...
Ask the Experts

Maraviroc, Isentress & Atripla?

It is time to change meds. My t-cells are down to 203 (12%) but I have a low, but measurable viral load (500 or so). I have the 69-insertion mutation, so nuks don't work - but I am sensitive to all other classes. I also am CCR5- tropic. I...
Edwin DeJesus, M.D., F.A.C.P.

Response from Edwin DeJesus, M.D., F.A.C.P.

Auchhh some how this story is not adding up well. If you have never taking a PI or an NNRTI, I assume that you were treated in the past only with nucleosides! That was not an acceptable treatment. If you developed the insertion 69, I also have to... Read more »

Maraviroc study or not?

Hi Dr. Daar, Thank you in advance for your time and energy for this site! I am a long term surviver, (21 years) and very drug experienced. I have reached another cross roads in my HIV journey. I have just completed the tests to see if I am R5...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
I will start by making some general comments and then specifics regarding your situation. Anytime someone is "failing" their antiretroviral treatment it is worth defining whether that is because their viral load has rebounded, because... Read more »

new development in the drug Maraviroc

Dear Dr.Bob,Hope you are well.I was just watching the news in England when a story about the HIV drug called Maraviroc was discussed. It was said that in a few months the drug will be available on the NHS (national health service in England). As you...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,Maraviroc is in a new class of anti-HIV drugs called "CCR5 Inhibitors." They target a very early stage in the infection process the cell-entry stage. These drugs have been in development for quite some time and maraviroc is primed to... Read more »

Maraviroc

My viral load has become detectable and my doctor would like to put me on Maraviroc and Isentress. I have been reviewing both of these drugs and I have some concerns with Maraviroc. I know it works on the CCR5 but what is known about the CCR5...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
The CCR5 receptor is a receptor on the CD4 T cell. It is used as a 2nd (or co-) receptor for HIV to enter the T cell. HIV may also use another co-receptor (called CXCR4) to enter the cell. Since maraviroc only blocks virus that use CCR5, it is... Read more »
Connect With Others

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies
In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »

ITS A FACT

Posted by Anonymous
Its a fact some of positive people lie about their status before sex. If you are going to have sex BE SAFE! dont believe people if they tell you they are negative, they may not be. ALWAYS PRACTICE SAFE SEX!!!!! I hope we learned something here.

Read more »

HIV FROM CONDOMS AFER FACT?

Posted by Anonymous, 2 Replies
What are the chances of catching hiv when:
You have sex with a male with the condom on, after he cums he pulls the condom off and you play around for around 10 minutes he puts his penis in you for a couple of seconds (about 2 inches)? Read more »

Facts II. WIndow Period

Posted by Anonymous, 3 Replies
Without having to travel so far away, you can find posts of Dr. Santana (The Body Spanish section) where he refers to the window period in a very similar way to what I said before,
In one of his posts he says: test at 3 months, at 6 months, at 9... Read more »

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