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Maraviroc Facts

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AIDS InfoNet

Maraviroc (Selzentry, Celsentri)

What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US and Celsentri elsewhere) was formerly known as UK 427,857. It is a drug used for antiretroviral therapy. It is manufactured by ViiV Healthcare. Maraviroc is the first "attachment inhibitor" drug. ...
Ask the Experts

Maraviroc, Isentress & Atripla?

It is time to change meds. My t-cells are down to 203 (12%) but I have a low, but measurable viral load (500 or so). I have the 69-insertion mutation, so nuks don't work - but I am sensitive to all other classes. I also am CCR5- tropic. I have...
Edwin DeJesus, M.D., F.A.C.P.

Response from Edwin DeJesus, M.D., F.A.C.P.

Auchhh some how this story is not adding up well. If you have never taking a PI or an NNRTI, I assume that you were treated in the past only with nucleosides! That was not an acceptable treatment. If you developed the insertion 69, I also have to... Read more »

ATRIPLA SEEMS NOT TO BE WORKING

Hello, let me say first of all thank you for all you do for folks like us who have been diagnosed with HIV. I have been on Atripla for 3 months. My latest viral load is 420000 with a cd4 of 10 whereas my initial VL was 322000 with a cd4 of 0 at the...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Thank you for your post and I hope you are feeling better after your hospitalization.I would definitely wait for the next test results. I assume you had a "baseline" resistance test done. If that showed susceptible virus it would be very unusual... Read more »

new development in the drug Maraviroc

Dear Dr.Bob,Hope you are well.I was just watching the news in England when a story about the HIV drug called Maraviroc was discussed. It was said that in a few months the drug will be available on the NHS (national health service in England). As you...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,Maraviroc is in a new class of anti-HIV drugs called "CCR5 Inhibitors." They target a very early stage in the infection process the cell-entry stage. These drugs have been in development for quite some time and maraviroc is primed to be the... Read more »

Maraviroc study or not?

Hi Dr. Daar, Thank you in advance for your time and energy for this site! I am a long term surviver, (21 years) and very drug experienced. I have reached another cross roads in my HIV journey. I have just completed the tests to see if I am R5...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
I will start by making some general comments and then specifics regarding your situation. Anytime someone is "failing" their antiretroviral treatment it is worth defining whether that is because their viral load has rebounded, because their immune... Read more »
Articles
AIDS InfoNet

Tropism Tests

What Is Viral Tropism? Some People "Naturally" Block the CCR5 Receptor How Is the Test Used? How Is Viral Tropism Measured? How Reliable Is the Test? What Do the Results Mean? Are There Problems With the Tropism Test? What Is... Read more »
AIDS InfoNet

Immune Therapies in Development

What Are Immune Therapies? Immune Stimulators Therapeutic Vaccines Anti-Inflammatory Approaches Gene Therapies NOTE: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog... Read more »
AIDSinfo

An Overview of Selzentry (Maraviroc, Celsentri)

mah-RAV-er-rock Brand Name: Selzentry Other Name(s): Celsentri, MVC, UK-427,857 Drug Class: Entry and Fusion Inhibitors Maraviroc, also known as Selzentry, is a type of medicine called an entry inhibitor. Entry inhibitors work... Read more »
AIDS InfoNet

Drug Names and Manufacturers

Reverse Transcriptase Inhibitors ("Nukes") Non-Nucleoside Reverse Transcriptase Inhibitors Protease Inhibitors Integrase Inhibitors Attachment and Fusion Inhibitors Antisense Drugs Immune Modulators None of these drugs can... Read more »
Connect With Others

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies
In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »

HIV FROM CONDOMS AFER FACT?

Posted by Anonymous, 2 Replies
What are the chances of catching hiv when: You have sex with a male with the condom on, after he cums he pulls the condom off and you play around for around 10 minutes he puts his penis in you for a couple of seconds (about 2 inches)? Read more »

Facts II. WIndow Period

Posted by Anonymous, 3 Replies
Without having to travel so far away, you can find posts of Dr. Santana (The Body Spanish section) where he refers to the window period in a very similar way to what I said before, In one of his posts he says: test at 3 months, at 6 months, at 9... Read more »