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Maraviroc Dosing

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Get the Facts

An Overview of Selzentry (Maraviroc, Celsentri)

mah-RAV-er-rock Brand Name: Selzentry Other Name(s): Celsentri, MVC, UK-427,857 Drug Class: Entry and Fusion Inhibitors Maraviroc, also known as Selzentry, is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking HIV from entering human cells. HIV/AIDS-Related Uses Maraviroc received accelerated approval on August 6, 2007, and traditional approval on November 25, 2008, by the FDA for the...
Ask the Experts

Muturation v TMC125 and Integrase

If you are able to enlighten me on the following I would be most grateful.I am currently taking the following drugs and have been for the past three years. I am currently on the Miraveroc trial and it has been determined that I am on a half dose...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
You are correct, you numbers are very good. There are many possibilities here. You could withdraw from the trial and up your maraviroc dose to a full dose twice daily (if I understand correctly you are only on half the recommend dose). That by... Read more »

efavirenz resistance

Hi DocLab tests just resulted in low level resistance to efavirenz. I am currently on truvada and efavirenz. My Doc wants to change to truvada and reyataz. I am concerned about the side effects of reyataz especially the yellowing of eyes and skin....
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Sorry to hear about the efavirenz (Sustiva) resistance.A switch to truvada + reyatazalone would not be a good move. You would also need to take a small (100 mg) dose of Norvir (ritonavir) to balance the regimen. Tenofovir, which is part of... Read more »

Unable to reach undetectable - clarification

Dear Dr McGowanThank you so much for your reply, much appreciated! You mentioned that intensifying treatment by adding a nucleoside such as truvada may help to knock down the vl to undetectable. I have just started (today) to take 3tc alongside my...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Thanks for the follow-up.Blood levels are important but must be based on the individual case. If your virus has a bit of resistance to treatment, a higher than average level may be needed. 3TC (lamivudine) is a nucleoside, truvada is a combination... Read more »

Unable to reach undetectable

I started hiv meds in March 2009 with a viral load of approx 120000 and cd4 230. My doctor suggested Truvada and Viramune. I took my meds religiously and initially they seemed to be working, with my viral load dropping to 68 and cd4 in the 450...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Dear worried in the UK,Occasionally we see people who have stubborn viral loads to fully suppress. The biggest worry that we as clinicians have is that the person may be missing doses. Since you know best that is not the issue here.It is true... Read more »
AIDS InfoNet

Maraviroc (Selzentry, Celsentri)

What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US... Read more »
U.S. Food and Drug Administration

Expanded Indication for Selzentry (maraviroc)

On November 20, 2009, the Food and Drug Administration approved a supplemental NDA to expand the indication for Selzentry (maraviroc) to include combination antiretroviral treatment of therapy naive adults infected with CCR5-tropic HIV-1 virus.... Read more »
Test Positive Aware Network


Common Name: maraviroc (formerly UK-427,857) Brand Name: Selzentry Class: CCR5 antagonist (a type of entry inhibitor) Standard dose: without food, with no food restrictions. The recommended dose varies depending on other... Read more »
The Well Project

HIV Drugs and the HIV Lifecycle

Table of Contents The Basics The HIV Lifecycle Approved HIV Drugs Combining HIV Drugs The Bottom Line The Basics HIV drugs cannot cure HIV but they can help you stay healthy by preventingthe virus from reproducing (making... Read more »
Connect With Others

Excessive Mastubation

Posted by Anonymous, 5 Replies
Ever since I found out that I'm poz, I've been spending a lot more time mastubating. Is that normal? Or could it be because of the amount of time I've been spending reading posts about sexual issues? Pleasing myself has become an every day thing... Read more »

Two weeks down and a life time to live

Posted by trulife, 2 Replies
Well's the end of two weeks on Atripla and so far things are going well. Side effects have been limited and are now subsiding. My biggest problem so far is swallowing the pill. I have always had trouble swallowing pills...go figure...a... Read more »


Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

Skipping Doses

Posted by chrisnxs, 2 Replies
Hello Everyone, can someone please elaborate on the severity of skipping meds? My bf is positive and has been on meds for about a year. He's on my insurance and it kills the price down to a point where he can get his meds pretty easily. I discovered... Read more »