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Maraviroc Dosages

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AIDS InfoNet

Maraviroc (Selzentry, Celsentri)

What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US and Celsentri elsewhere) was formerly known as UK 427,857. It is a drug used for antiretroviral therapy. It is manufactured by ViiV Healthcare. Maraviroc is the first "attachment inhibitor" drug. When HIV...
Ask the Experts

Maraviroc

My viral load has become detectable and my doctor would like to put me on Maraviroc and Isentress. I have been reviewing both of these drugs and I have some concerns with Maraviroc. I know it works on the CCR5 but what is known about the CCR5...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
The CCR5 receptor is a receptor on the CD4 T cell. It is used as a 2nd (or co-) receptor for HIV to enter the T cell. HIV may also use another co-receptor (called CXCR4) to enter the cell. Since maraviroc only blocks virus that use CCR5, it is... Read more »

maraviroc

hi drgood morninghope all is well on your side.i am a male of 30 newly diagnosed with hiv during a blood donation camp.in couple of days my lab results for cd4 and viral load will be out and i will see an hiv specialist for the drug regimen.i read...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is comparativey little info about use of CCR5 inhibitors like maraviroc for initial treatment of HIV infection. Since the success rates for initial therapy with current often simple (once daily ) regimens is now fairly high (often > 90%)... Read more »

Taking Maraviroc

Hello,im now taking crixivan, combivir and bactrim daily..my CD4 around 100 and viral load 6000+my doc suggest me to change my treatment to maraviroc..is it maraviroc suitable for Hep-C/Heamophilia patient with HIV?and what ur suggestion?...
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
Thank you for your post. It is very unusual in the current era to find someone on crixivan with NRTIs in your situation. Clearly if you are taking your medications and have detectable viral load on this regimen you should have drug resistance... Read more »

Celzentry (maraviroc) and Issentress + Truvada?

Dear Dr. Henry,My doctor wants to put me on celzentry and Isentress and Truvada. I would prefer celzentry or isentress, plus truvada. I was surprised when he told me he wanted to put me on both, plus truvada. He feels I need "more...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
If you have not had a CCR5 Trophile test then it is tough to have confidence that maraviroc + Truvada alone would be able to maintain suppression so that is perhaps why the raltegravir is being considered as well. The barrier to resistance for... Read more »
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Eviplera and Maraviroc Side Effects

Posted by philfromoz, 1 Reply
Is Eviplera and Complera the same thing? Anyway I'm taking it and Maraviroc (Selzentry in the US and Celsentri elsewhere). I have been on Eviplera for 12 months and the Maraviroc was added in January. I have no idea why something wasn't working or... Read more »

high lipids

Posted by Anonymous
Has anyone tried this product http://www.policosanol.com/monograph.htm#dosage
if so please post results/side effects
Thanks

Read more »

Interferon Roferon Peginterfeon Side Effects

Posted by Claude, 1 Reply
Hi guys,

Did any of you go through bilogical treatment with any kind of Interferons. If you did could you please tell me more about your dosage and side effects?

I am currently on INTRON A and it's a living hell. I don't know what to do anymore.... Read more »

NAC

Posted by Anonymous, 2 Replies
Poz 16 years. Should i be taking NAC? Any stories, suggestions? good /Bad? What form and dosage? Thanks! Read more »