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Lopinavir/Ritonavir And Hiv

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Get the Facts
AIDSinfo

An Overview of Kaletra (Lopinavir/Ritonavir)

...Kaletra Other Name(s): Aluvia, LPV/RTV, LPV/r Drug Class: Protease Inhibitors Lopinavir/ritonavir, also known as Kaletra, is a type of medicine called a protease inhibitor (PI). PIs act by blocking protease, a protein that HIV needs to make more copies of itself. HIV/AIDS-Related Uses Lopinavir/ritonavir in capsule and oral solution form was approved by the FDA on September 15, 2000, for use with other antiretrovirals in the...
Ask the Experts

why would i get kaletra and prezista (?) for exposure only?

is it normal to receive a regimen of kaletra (2 tabs 2 times a day) along with what i think is prezista (big orange pill) just to reduce my chances of contracting hiv after exposure? how long would you thnk is normal for sucha regimen?
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Hello and thank you for your post.Since Prezista (darunavir) and Kaletra (lopinavir/ritonavir) are both HIV protease inhibitors, there is rarely any circumstance where both would be prescribed at the same time. Post-exposure prophylaxis Read more »

clenbuterol and retroviral treatment.

hi I have just started my HIV treatment lopinavir ritonavir combine with emicitrabine tefonovir. I use regularly clenbuterol as part of my work out regime. Do you think this can affect the treatment?
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...There is no data on interactions between this HIV regimen and clenbuterol that I am aware of. However, caution regarding side effects or lab abnormalities is the order of the Read more »

ATRIPLA, NOT GOOD?

I just read the A5142 study which compared efavirenz (EFV, Sustiva, Stocrin) + two nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs), lopinavir/ritonavir (LPV/r, Kaletra) + two NRTIs and efavirenz + lopinavir/ritonavir without any...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...lipoatrophy.On to your specific question: is Atripla NOT GOOD? Certainly it's proven itself to be both a convenient and effective anti-HIV therapy. In a different recent study, the efavirenz (Sustiva) containing arm was more effective in... Read more »

Respuesta al Dr. Natterstad

Hola Dr. Steven:Espero que ests bien al recibo de estas cortas lneas.La respuesta a las (2) preguntas que me formulaste en mi consulta del pasado 3 de agosto de 2007 sobre Nuevo rgimen son:1. Tomo Kaletra (Lopinavir/Ritonavir) 200mg/50mg dos...
Steven M. Natterstad, M.D.

Response from Steven M. Natterstad, M.D.

Frascino Medical Group
Hola ngel,Gracias por tus respuestas. Todava no lo tengo claro porque ests tomando los dos Kaletra y Sustiva. No se debe a que tu virus es resistente al ritonavir, porque en tu caso lo tomas solamente para potenciar lopinavir y no como un componente... Read more »
Articles
U.S. Centers for Disease Control and Prevention

Prospective, Randomized, Open-Label Trial of Efavirenz vs. Lopinavir/Ritonavir in HIV+ Treatment-Naive Subjects With CD4+ Less Than 200

...or LPV/r groups was stratified by baseline CD4+ count (up to 100 or above 100). At 48 weeks, the primary endpoint was plasma HIV-1 RNA below 50 copies/mL by intention-to-treat analysis. Among the EFV and LPV/r groups, 85 percent of whom were... Read more »
The Body PRO

Response to Lopinavir/Ritonavir in HIV-Infected Patients Coinfected With Hepatitis C and/or Hepatitis B

...It is well known that HIV-infected patients with hepatitis C virus (HCV) are at greater risk of antiretroviral-induced hepatotoxicity. Some studies suggest Read more »
The Body PRO

908 Plus Lopinavir/Ritonavir Does Not Appear to Be a Viable Regimen for HIV-Infected Patients

...in this study. In fact, the amprenavir and ritonavir concentrations observed in this study in the 908/ritonavir arm, and the lopinavir and ritonavir concentrations in the lopinavir/ritonavir arm were similar to what has already been published... Read more »
The Body PRO

Unboosted Atazanavir Better on Insulin Sensitivity Compared to Lopinavir/Ritonavir

...without ritonavir (RTV, Norvir), has less of an impact on this measurement when compared to lopinavir dosed with ritonavir. Thirty HIV-negative persons were enrolled in this study. They took either atazanavir 400 mg once a day, or three capsules... Read more »
Connect With Others

New Drug - TMC114

Posted by Survivor, 1 Reply
...Cost More Than Kaletra, Advocates Urge We may be only days away from an announcement that the U.S. has approved a new HIV medication: TMC114 (darunavir), a protease inhibitor that may be especially helpful for people with resistance to... Read more »

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

about to start treatment

Posted by Anonymous, 4 Replies
hi. kinda scared.. about to start treatment. My dr wants to use an induction/maintenance strategy starting with an intense four-drug Kaletra (LPV/r, lopinavir/ritonavir)-based regimen along with Combivir [AZT/3TC] + Viread [tenofovir]. can you tell... Read more »

HIV / AIDS DOCS

Posted by Survivor, 1 Reply
...What do HIV/AIDS Doc's do, when they are not seeing you? http://www.thebody.com/thebody/ukraine.html Ben Young, M.D. In Ukraine, Clinicians Read more »