Invirase Side Effects

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Saquinavir (Invirase)

What Is Saquinavir? Saquinavir, also called Invirase, is a drug used as part of antiretroviral therapy (ART). There used to be a version called Fortovase that is no longer made. Saquinavir is manufactured by Roche Laboratories. Saquinavir is a protease inhibitor. These drugs prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV into specific pieces needed to build a new virus....

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Invirase-Fortovase

Dear Doctors,I have a question concerning my treatment.I have been on Invirase and Combivir since 1999, July. Fortunately my viral load is still below 50 copies. My doctor insists on switching to Fortovase as a better version of saquinavir. I am...

Response from Andrew T. Pavia, M.D.

University of Utah, School of Medicine

Maria,You definitely should not stay on Invirase, in my opinion. The drug levels of saquinavir are generally so low that resistance is common, and resistance to saquinavir is not a good thing to have. You have many choices. Since you did not mention... Read more »

new kaletra and invirase

I have been on a medication holiday for about 5 month and needed to go back on meds again. My doctor put me on the new Kaletra (tablets) and Invirase plus Kivexa. Eventhough I have taken both PI s before in their original version (but never...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

The situation is more complex due to the Kivexa (abacavir + 3TC= Epzicom in US) and the issue of possible abacavir hypersensitity. Did your MD screen for HLA B5701 status (helps predict adverse reaction to abacavir). I have had numerous patients on... Read more »

norvir + invirase the best posology ?

I have been receiving HIV treatment for 3 years now. After using DDI and retrovir for a year an a half, I stopped regimen fora while because I got a lymphom (non hogdkin). Then since july I take D4T and 3TC. But now my T4 are quite low 90 an dviral...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

I had to look up the word "posology" because it is not commonly used in English.I learned that it is the science of dosing. So thank you for contributing to myeducation. Now for your question . . .I like your doctor's approach very... Read more »

Missed Morning Dose of Kaletra & Invirase

Hello,I apologize upfront for any duplications if this question has been asked before -?? In any case, in 1995, at age 36, I was diagnosed with HIV. My physician initially started me on AZT. Later, he changed to Viracept, Epivir and Zerit. I...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

Don't worry. Your single mishap is highly unlikely to have led to any change in resistance of the virus. If you continue to be as diligent as you have been about taking your meds, I suspect you will continue to do well.Further good news is... Read more »

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anyone taking Isentress and Invirase combination?

Posted by nevereasy

Isentress is a relatively new therapy. My Dr just added it to my mono therapy of Invirase (boosted with Norvir). I have been undetectable for two years on the Invirase but my Tcells never get over 300. He added Isentress. I have had bad reflux ( not... Read more »

Solution to Atripla Side Effects (at least for me)

Posted by Wiilock, 3 Replies

Hey all, I have been on the "wonder pill" for about 3 years now. Previously was on norvir boosted invirase/truvada combo but the GI problems finally were too much.
Anyway I want to briefly recap what I've learned from some of my homeopathic... Read more »

Liver Function

Posted by NYRN, 1 Reply

I'm taking viread, invirase, didanosine, zidovudine and valtrex and my latest labs indicate high on the liver screens. Has anyone had any liver issues - I don't drink so it's not that! Read more »

PI Monotherapy advice

Posted by logopolis, 2 Replies

Admin OptionsEdit Discussion Close Discussion Edit Your Tags
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Delete Discussion Hi,

My partner has been asked to take part in a clinical trial - Protease Inhibitor monotherapy versus Triple Therapy.

Just gathering some info before he signs up.... Read more »

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