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... Common Name: etravirine Brand Name: Intelence Class: non-nucleoside analogs (also called non-nucleoside reverse transcriptase inhibitors, NNRTIs or non-nukes) Standard dose: Two 100 mg tablets twice daily, with food. Take missed dose as soon as possible, unless...occur with hepatic (liver) failure, and fatality due to Stevens-Johnson Syndrome, erythema multiforme, and toxic epidermal necrolysis (TEN), all skin disorders....
Ask the Experts

What type of meal with Intelence?

...I have been on Intelence for about a year along with other meds. Does the meal before taking Intelence need to be a certain composition? I like eating
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
...Dennis,Thanks for your question. Taking Intelence with food increases its absorption from the stomach so that it can get a better blood level to be effective in killing the HIV. Read more »

Muscle and Joint Pain -- Intelence

...I have been taking Intelence since it was initially being tested. I've recently developed muscle pain (all over) and more specifically joint pain in both... elbows. Could this be due to Intelence? The other drugs I am taking for HIV are...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
The rate of myalgia/myositis with etravirine in clinical studies was very low (< 1%) so it can happen but generally would look for another explanation. rates of muscle disorders for your other HIV meds is similarly low. Looking at muscle enzyme... Read more »

Intelence and erection medicine

...Recently switched to Intelence and Truvada. Are there any erection drugs that will work. My doc said viagra, cialis, etc won't work. Is it true that only the... level of the erection medicine goes down, or could the Intelence level be decre ased...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
I haven't seem much use of only etravirine + Truvada (etravirine usually used with boosted protease inhibitor such as darunavir/Prezista). Etravirine could decrease levels/effectiveness of the viagra/cialis drugs--not much publised data on that. I... Read more »

Re: Intelence+Kivexa (Moscow Russia)

...not Combivir. What do you think about this comb for me? What is more hard for liver, combivir or Kivexa? Some doctors say that Intelence is not a med for the first line but it is only while. Soon it could be so, after new examinations. Is it?
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Kivexa usaully as well or better tolerated than Combivir overall. Etravirine in the US can be used early or initially in treatment if the prescribing doctor feels it is warranted (little use in that manner so far since many other options available... Read more »
U.S. Food and Drug Administration

Newly Approved Intelence (Etravirine) Dose May Halve Pill Burden

... On December 22, 2010, the Food and Drug Administration approved a new 200 mg Intelence (etravirine) tablet. Intelence was originally approved in 2008, in only a 100 mg tablet formulation. The new 200 mg dosage form... can help reduce pill burden... Read more »
U.S. Food and Drug Administration

Intelence (Etravirine) Label Revised to Include New Drug-Drug Interaction Information

... FDA recently updated Intelence (etravirine) label to include drug-drug interaction information between etravirine and fluconazole, voriconazole, lopinavir/; therefore, etravirine and fluconazole or voriconazole should be... Read more »
Project Inform

New Warning of Serious Intelence Side Effect

... In August 2009, the FDA announced an updated side effect warning for Intelence (etravirine), the newest approved NNRTI. This comes after reports of severe allergic reactions, usually occurring during the...use the drug and experience these side... Read more »
Tibotec Therapeutics

HIV/AIDS Update -- New Intelence Labeling: Severe Skin and Hypersensitivity Reactions to inform you of an important safety update to the Severe Skin Reactions WARNINGS AND PRECAUTIONS section (5.1) of the INTELENCE (etravirine) tablets prescribing information. Specifically, the existing Warning and Precaution regarding... Read more »
Connect With Others

anyone having problems with Intelence????????

Posted by laguy38v
...I started on Intelence over 8 days ago and I broke out in a rash all over my body. My Doctor wants me to continue and see if the rash will go away once...problem? He put me on presnisone to help deal with the itching. This drug is one of my last... Read more »


Posted by laguy38v, 2 Replies
Hi has anyone had a rash because of it and if so did it finally go away? I have a horrible rash after 8 days and my Doctor wants me to stay on it with the hope it will go away. Thank you for any information. Read more »

Question for males on Intelence and/or Isentress.

Posted by Monchhichi, 1 Reply
Are there any side effects that you have been noticing? My husband just started these at the beginning of April and he is having one side effect that is not listed as a possible side effect of either med. They both have the basic side effects... Read more »

Isentress and Intelence side effects

Posted by nevereasy
Anyone taking these two drugs together? One or the other?. I seem to be extremely fatigued and weak. Additionally I am off balance also have a marked increase in my need to take a lorazapam ( anti anxiety) . Anybody else have any of these problems? ... Read more »