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Intelence Dosing

Here's a taste of what has to offer on this topic:
U.S. Food and Drug Administration

Newly Approved Intelence (Etravirine) Dose May Halve Pill Burden

On December 22, 2010, the Food and Drug Administration approved a new 200 mg Intelence (etravirine) tablet. Intelence was originally approved in 2008, in only a 100 mg tablet formulation. The new 200 mg dosage form can help reduce pill burden for... Read more »
U.S. Food and Drug Administration

Intelence (Etravirine): Pediatric Dosing Recommendations and New Scored 25 mg Tablet for Pediatric Dosing

On March, 26, 2012, the Food and Drug Administration approved dosing recommendations for INTELENCE┬« (etravirine) for treatment-experienced pediatric patients 6 to 18 years of age and weighing at least 16 kg. In addition a new scored 25 mg tablet... Read more »
U.S. Food and Drug Administration

Intelence (Etravirine) Label Updated to Reflect Dosing Data Through 48 Weeks

On November 24, 2009, FDA approved revisions to the INTELENCE (etravirine) labeling to include updated results through 48 weeks of dosing for the two Phase 3 trials TMC125-C206 and TMC125-C216 in treatment-experienced patients. This constitutes the... Read more »
Ask the Experts

Once daily dosing of etravirine (Intelence)?

I was on Efavirenz and Truvada but recently switched to Etravirine and Truvada because of sleep/dream/emotional issues. I saw some research that suggested the 400 mg dose of Efavirine could be taken safely once a day...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
There is a study with a new formualtion of Intelence that would be given once a day. We are waiting for final results and then the new form would have to get approval from the FDA. The current pills should not be taken once a day. Stay tuned.Joe... Read more »


My doctor has just prescribed 4x100mg etravirine ONCE a day. I don't see this in the product leaflet or online desription, where 2x100 TWICE a day is recommended. I am very worried... Its Friday and I can't speak to him till Monday! What...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
You are correct, the standard dosing of etravirine is 200 mg twice daily. I would take it that way unless you can clarify it with your doctor. This would be especially true if your virus had any previous resistance to medicines such as efavirenz... Read more »

Intelence (question from Russia Moscow)

Dear Doc, I m from Moscow Russia,the quest is: my doctor give me intelece+Kivexa for the first line, is it possible for people who never take therapy like me? My analises: CD - 276, 18%, viral - normal 4500 (we have much in Russia is 60000 and more...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
etravirine (Intelence) is currently awkward to take (2 pills twice a day) and has been mostly studied in patients with treatment experience/resistance. It would be expected to work well in patients with little/no resistance (including your... Read more »


Hi Dr. Henry,I have been on Atripla for about 5 years and have had sleep issues on and off for that time. I also work odd hours so that probably does not help with a good sleep pattern. I switched my dosing to 11 am and found that to help with...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There is yet little data on once a day dosing for etravirine. Though the etravirine + Truvada option may be reasonable, other choices to consider (with more data available supporting the safety of a switch in absence of known drug resistance) would... Read more »
Connect With Others

Isentress and Intelence side effects

Posted by nevereasy, 2 Replies
Anyone taking these two drugs together? One or the other?. I seem to be extremely fatigued and weak. Additionally I am off balance also have a marked increase in my need to take a lorazapam ( anti anxiety) . Anybody else have any of these problems? ... Read more »

anyone having problems with Intelence????????

Posted by laguy38v
I started on Intelence over 8 days ago and I broke out in a rash all over my body. My Doctor wants me to continue and see if the rash will go away once my body gets use to the new drug. Has anyone had the same problem?
He put me on presnisone to help... Read more »


Posted by laguy38v, 2 Replies
Hi has anyone had a rash because of it and if so did it finally go away?
I have a horrible rash after 8 days and my Doctor wants me to stay on it with the hope it will go away.
Thank you for any information. Read more »

Question for males on Intelence and/or Isentress.

Posted by Monchhichi, 1 Reply
Are there any side effects that you have been noticing? My husband just started these at the beginning of April and he is having one side effect that is not listed as a possible side effect of either med. They both have the basic side effects... Read more »