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An Overview of Crixivan (Indinavir)

... in-DIN-a-veer Brand Name: Crixivan Other Name(s): IDV, Indinavir sulfate, L-735,524, MK-639, Sulfato de indinavir Drug Class: Protease Inhibitors Indinavir sulfate, also known as Crixivan, is a type of medicine called a protease inhibitor (PI). PIs act by blocking protease, a protein that... HIV needs to make more copies of itself. HIV/AIDS-Related Uses Indinavir was approved by the FDA on March 13, 1996, for use...
Ask the Experts

switching from indinavir to Lopinavir/r

...I have a patient has been well controlled with Indinavr+ AZT+3TC. But now Indinavir is not available. Will it be acceptable to use Lopinavir/r with same 2 NRTIs. The patient had previous exposure to Squinavir
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Should not be a problem at all. Read more »

Indinavir sulfate

...Dear Doctor,I have a question about the dose of Indinavir sulfate.According to a book about HIV/AIDs treatment (Published by POZ organization), the dose of Indinavir is 800mg three time...twice-daily dose is not recommended due to viral load...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Thanks for your post.Indinavir (Crixivan) can be dosed either way-- without ritonavir (Norvir) boosting, the medication is dosed every 8 hours, fasting. Indinavir Read more »

nelfinavir+indinavir, is it possible?

...Nelfinavir+indinavir, is it possible? Nelfinavir+indinavir, is itpossible?
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School's possible.BUT, it hasn't been tested so we wouldn't know what doses to use. Also,since nelfinavir is taken with food and indinavir is taken on an emptystomach, you'd be taking six different doses per day. Read more »

pep doseage confusion Indinavir 2 or 3 times day?

...Been prescribed PEP Combivir and Indinavir both at 2 doses per day.However have read here and at WHO website that Indinavir should be taken 3 times daily.Currently taking
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hello,The correct dose of indinavir is 800 mg every eight hours in a fasting state (one hour before or two hours after a meal). You should also drink at least six... eight-ounce glasses of water per day (48 oz) to prevent indinavir-associated... Read more »
The Body PRO

Late Breaker No. LB16: Phase III, Multicenter, Randomized, Open-Label Study to Compare the Antiretroviral Activity and Tolerability of Efavirenz (EFV) + Indinavir (IDV), versus EFV + Zidovudine (ZDV) + Lamuvidine (3TC), versus IDV + ZDV + 3TC at 48 Weeks (Study DMP 266-006)

...counting the events on study. Those who reached PCR    OBS LOCF NC=F EFV/ZDV/3TC 98% 86% 71% EFV/IDV 83% 66% 53% IDV/ZDV/3TC 86% 61% 48% Statistically, there is a difference (p to suppress viral... Read more »
The Body PRO

Session 50, Abstract 379: Combination Therapy with AZT + 3TC + Indinavir vs. d4T + 3TC + Indinavir in Pretreated Patients with Less than 200 CD4/mm 3

...non-randomized study, Dr. Rubio and colleagues looked at the efficacy and tolerance of combination therapy with AZT + 3TC + indinavir as compared to d4T + 3TC + indinavir. They enrolled forty-four pre-treated patients (either AZT and/or ddI... Read more »
AIDS InfoNet

Indinavir (Crixivan)

... What Is Indinavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With... Other Drugs? What Is Indinavir? Indinavir is a drug used as part of antiretroviral therapy... Read more »
The Body PRO

Poster Session 22404: Pharmacokinetic Interaction Between Nevirapine and Indinavir and Correlation with Antiviral Activity

...Nevirapine and indinavir are metabolized by the same enzyme 'pathway' in the liver -- called the "P450" enzyme -- and therefore have the potential of...Robert Murphy, 24 patients who were either naïve or on stable nucleoside RTI treatment began... Read more »
Connect With Others

PEP Question

Posted by agny, 1 Reply
...PEP. They didn't favor the idea becasue of all the side effects. Just a question about the prescription. They gave me three: Indinavir Sulfate: every 8 hours Nevirapine: Every 12 hours Abacavir Sulfate: Twice a day Wanted to make sure if there... Read more »

mas efectos del los trataminetos

Posted by Anonymous, 1 Reply
...Retrovir), d4T (estavudina, Zerit), 3TC (lamivudina, Epivir), abacavir (Ziagen), nevirapina (Viramune), efavirenz (Sustiva) e indinavir (Crixivan). Read more »

What do you think?

Posted by Anonymous, 2 Replies
...Journal of Virology, researchers report an astounding discovery: The protease inhibitor drugs Crixivan (indinavir) and Invarase (saquinavir) caused T cell death in healthy HIV negative donor ... Read more »

does your feet and bones hurt too??

Posted by Anonymous
...t-cell was 160 and my viral load was 490,000.00.Now my t-cell is 478 and I'm undectable.I take indinavir,zerit,and lamivudine.Also a number of other PILL'S to help with soreness,dizzyness etc.I get... Read more »