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Indinavir Side Effects

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AIDSinfo

An Overview of Crixivan (Indinavir)

...ketoconazole, or rifabutin. Individuals should always take indinavir as prescribed by their doctor. Contraindications Individuals should tell a doctor about any medical problems before taking this medicine. Possible Side Effects Along with its desired effects, indinavir sulfate can cause some serious unwanted effects, including kidney stones. A doctor should be notified if an individual (especially a child) taking this medication...
Ask the Experts

Will switching to Atazanavir reverse the weight gain and fat deposits?

it has recently been recommended that I stop taking nelfinavir and replace it with atazanavir boosted with ritonavir in order to halt the progression of lipodystrophy. I will continue to take nevirapine and 3TC. What is the evidence that this will...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
This is an interesting question. The regimen you are now taking carries a limited risk of any lipodystrophy. This being said, there are a few case reports of reversal of body shape abnormalities following a switch from another protease inhibitor... Read more »

Sustiva Efficacy

After 11 great years on Crixivan/Combivir, my doctor is changing me to Sustiva/Combivir to avoid long term kidney issues. Undetectable since 1996. Very adherent patient. Concerned with long-term efficacy of Sustiva. Also, any issues with lipo...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...indinavir (Crixivan) and Combivir. If you haven't had difficulty with adherence (which is quite an issue with indinavir) or side effects after 11 years, it would be hard for me to predict that you'll have problems in the future.Nonetheless, it... Read more »

re: honesty when side effects

Regarding the questioner who asked why docs aren't honest regarding side effects from the meds, I can only say my docs have always laid everything out and I made the decisions. I tested positive 21 years ago. I started meds 10 years ago this month....
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...experiences-- even ones with medications like AZT,3TC and indinavir-- a regimen that today we'd call very difficult and side effect-prone.Yes, there are many treatment options today. It should be possible for the vast majority of first- and... Read more »

Afiran Desperate for Aswers

I just discovered my status and I am shocked how little Doctors know here. My symptoms were mainly confusion, dizzyness and these are still there but less. I was prescribed with Lexotan for 3 days and the symptoms dissapeared only to resurface...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
...good for you, if taken twice a day as recommended. Indinavir three times a day on an empty stomach is difficult. I would consider trying the nevirapine, zidovudine and the lamivudine again and having your CD4 cell count checked every month for... Read more »
Articles
AIDS InfoNet

Indinavir (Crixivan)

... What Is Indinavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Indinavir? Indinavir is a drug used as part of antiretroviral therapy... Read more »
The Body PRO

Late Breaker No. LB16: Phase III, Multicenter, Randomized, Open-Label Study to Compare the Antiretroviral Activity and Tolerability of Efavirenz (EFV) + Indinavir (IDV), versus EFV + Zidovudine (ZDV) + Lamuvidine (3TC), versus IDV + ZDV + 3TC at 48 Weeks (Study DMP 266-006)

...counting the events on study. Those who reached PCR    OBS LOCF NC=F EFV/ZDV/3TC 98% 86% 71% EFV/IDV 83% 66% 53% IDV/ZDV/3TC 86% 61% 48% Statistically, there is a difference (p to suppress viral... Read more »
The Body PRO

Combining Indinavir with Ritonavir

...less frequent -- doses could be given without lowering blood levels. Lower blood levels generally mean less antiretroviral effect. 9 men and 1 woman actually completed the 17-day study; three discontinued because of side effects, while three... Read more »
Canadian AIDS Treatment Information Exchange

Protease Combinations: Ritonavir and Indinavir One Year Later

...achieved a viral load of fewer than 50 copies was as follows: ritonavir with indinavir -- 64% indinavir alone -- 70% Side Effects The side effects listed affected the following proportion of subjects in each group: Nausea and/or... Read more »
Connect With Others

PEP Question

Posted by agny, 1 Reply
...already mentioned I went to the emergency room to get a prescription for PEP. They didn't favor the idea becasue of all the side effects. Just a question about the prescription. They gave me three: Indinavir Sulfate: every 8 hours Nevirapine:... Read more »

Side effects

Posted by abirch, 1 Reply
...am an African American women who has been hiv+ for 10 years I have been taking medication for 8 years. Currently I am taking indinavir, combivir, and norvir. My skin is gradually getting darker, and my lips are constantly dry, swollen and... Read more »

information

Posted by Anonymous, 1 Reply
...treatment. A study sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) in Uganda found a highly effective and safe drug for preventing transmission of HIV from an infected mother to her newborn. Independent studies... Read more »

Picking Combinations

Posted by Anonymous, 2 Replies
I am about to begin treatment and am really at a loss. What is the combination of choice?? Can anyone tell me? Is sustiva really that great? RJ Read more »