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Spotlight Series: HIV Stigma and Discrimination

HIV RNA Absence Of Antibodies

Here's a taste of what has to offer on this topic:
Get the Facts
U.S. National Institute of Allergy and Infectious Diseases

The Evidence That HIV Causes AIDS

...Med 1994;121:886). In addition, through December 1999, the CDC had received reports of 56 health care workers in the United States with documented, occupationally acquired HIV infection, of whom 25 have developed AIDS in the absence of other risk factors. The development of AIDS following known HIV seroconversion also has been repeatedly observed in pediatric and adult blood transfusion cases, in mother-to-child transmission, and in studies...
Ask the Experts

Adopting Child with initial positive then negative tests

We are considering adopting a child with the following results: 02/04 born;04/04 negative PCR HIV;07/04 negative PCR HIV;09/04 positive EIA to HIV;12/04 negative EIA to HIV;08/05 hiv monitoring stopped. What does it all mean?
Katherine Luzuriaga, M.D.

Response from Katherine Luzuriaga, M.D.

University of Massachusetts, Medical School
...their antibodies (including antibodies to HIV) to their babies. However, only 25-30% pass the virus to their babies in the absence of antiviral therapy. If moms and babies receive antiviral therapy, transmission rates are much lower. Since... Read more »

Babie and HIV positive mother

My wife and I are planning to adopt a baby. We find out that the baby we want, the mother when she went to give birth came out as HIV positive. The baby is 5 months now. They have done two preliminary tests and so far have come out negative to HIV....
John L. Sullivan, M.D.

Response from John L. Sullivan, M.D.

University of Massachusetts, Medical School
...In the developed world we have well established tests which can tell if a baby is HIV infected by one month of age in the absence of breast feeding. These tests are extremely sensitive and can detect HIV RNA or DNA, that is they detect the virus... Read more »

PCR RNA / Antibodies

Hi doc.Have read that a person can have PCR RNA test result < 50 copies / ml. and still be HIV Positive.If this is a result for the immune system's ability to control viral replication - would this meen that immune system when "fighting the virus"...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...There are a few people who have viral loads of < 50/ml, in the absence of therapy. They would indeed by people who had good immunologic control of the virus (antibodies and cytotoxic T cells). Although Read more »

Viral Load Not Reliable after period of time???

My gynecologists tells me that the PCR RNA is not reliable. Now after having a negative antibody test at 16 wks and a undetectable (<400 copies) at 18 weeks, I am freaking out. He says that the viral load could very well be undetectable at 18 weeks...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
...An undetectable viral load in the ABSENCE of antibodies after 4 months of exposure equals NO HIV infection. Read more »
New York State Department of Health AIDS Institute

Diagnostic, Monitoring and Resistance Laboratory Tests for HIV

...antibodies to HIV-1 and HIV-2. Three advantages to these assays are as follows: Collection of the sample is noninvasive The absence of needles increases the safety for the personnel collecting the sample Disposal of potentially infectious... Read more »
U.S. Centers for Disease Control and Prevention

Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents

...54,56,69-72 . The second group includes OIs that occur >12 weeks after initiation of ART among patients with suppressed HIV ribonucleic acid (RNA) levels and sustained CD4 + counts >200 cells/ ยต L 73,74 . Determining whether these represent a... Read more »
The Body PRO

Can HIV be Eradicated?: Report on Dr. David Ho's Presentation

...blunting if not lack of production of gp120 and p24 antibodies as compared to untreated patients. In 7 cases there was also an absence of fresh unstimulated cytotoxic T lymphocyte (CTL) response in their peripheral blood mononuclear cells. Ho... Read more »
Gay Men's Health Crisis

Stalking HIV Immune Dysregulation

...invader. The DTH test in current use measures the diameter of the induration to gauge the presence and extent of immune memory. The absence of an immune response, indicated by little or no induration, is referred to as anergy (a state of immune... Read more »
Connect With Others

Test results to HIV and HCV

Posted by Anonymous, 2 Replies
...concentration of p24 antigen was 250 ng per liter, the HIV Western blot assay had no positive band, and an enzyme immunoassay for antibodies to HIV was negative. The test for HIV antibodies first became positive on day 31, when the HIV Western... Read more »


Posted by Anonymous
...presents with fever of unknown cause. The diagnosis is based on a positive HIV-1 RNA level (more than 50,000 copies per mL) in the absence of a positive enzyme-linked immunosorbent antibody assay (ELISA) and confirmatory Western blot antibody... Read more »

Accuracy of PCR

Posted by Anonymous, 2 Replies a 6 month ELISA (and certainly a 3 month ELISA). A thought occurred to it possible that one could develop enough antibodies to make the PCR undetectable at 7.5 weeks? The Quest test says it measures down to 10 copies. Do antibodies... Read more »

elisa vs. pcr

Posted by Anonymous
...Whether extended follow-up is indicated in other circumstances (e.g., exposure to a source coinfected with HIV and HCV in the absence of HCV seroconversion or for exposed persons with a medical history suggesting an impaired ability to develop an... Read more »