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An Overview of Fuzeon (Enfuvirtide, T-20)

en-FYOO-vir-tide Brand Name: Fuzeon Other Name(s): T-20 Drug Class: Entry and Fusion Inhibitors Approved Use: Treatment of HIV Infection WARNING: Enfuvirtide causes injection site reactions. Almost all people get injection site reactions with enfuvirtide, which usually are mild to moderate but occasionally can be severe. Reactions on the skin where enfuvirtide is injected include: Itching. Swelling. Redness. ...
Ask the Experts

Stopping Fuzeon to Save Fuzeon

cocktails to find one that helped me achieve an undetecable, sometimes <400 sometimes <48 never >400, VL thanks to Fuzeon, my ID Dr wants to stop Fuzeon - due to numerous Inj Site Reactions and loss of fat - for Raltegravir. Also, he wants...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
There is too little experience with these drugs to be confidant in any answer to the questions you are asking, but one recent report does suggest that the switch that your doctor is proposing is safe in the short term. At the recent CROI meeting,... Read more »


i would like to know if a side-effect to using fuzeon can make the skin become more oily and the sperm more gluey and sticky or it can happen also from high level of triglycerides...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
I'm not aware of the side effect with the sperm. As for the skin, reactions ar quite common, but are usually at the site of the injection and quite self-limited. On occasion, there can be a more generalized rash, but I have not heard of it... Read more »

FUZEON _Con fuzeon!

Hi and Thank you for being there for all of us! Thank you for accepting a bit of colorful expression enclosed.I'm HIV+ for 161/2 years and I have CD4 of 397 and vl of 14,000 to 44,000 and I've had to change doctors lately (long history -...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
comments. It's always good to hear that our forums are informative and worth recommendation to others. Confusion (or confuzeon) is not unusual for people in your situation. I like the pun (though I'm sure that the folks at Roche might... Read more »

Fuzeon arternatives

I am currently taking Fuzeon, Prezista, Novir and Issentress. I was taking Trizivir and then switched to Atripla. My question is if the Fuzeon et al quit...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
each of your previous regimens.It is possible (though not certain), that you'll have other treatment alternatives to T20 (Fuzeon) that could be combined with the Norvir/Prezista + Isentress. Ask your doctor for copies of your resistance tests... Read more »
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Posted by Monchhichi, 2 Replies
Just a question I want to get feedback on...To anyone on Fuzeon...What type of side effects are you getting and injection site reactions? Does anyone have any tips they can give on ISR's? My husband has been on Fuzeon for over a year now and any... Read more »

New Fuzeon needles

Posted by Monchhichi
Just wanting to se what everyone who is on Fuzeon thinks of the new needles that are being supplied with the kit. Do you like them better or not? I know I personally do not like them. My husbands doctor is wondering and hopefully your input will... Read more »

Question about flying with Fuzeon and needles

Posted by rickincattco, 2 Replies
I would like to hear about peoples experiences with flying with Fuzeon viles and needles. With the events of last week I am wondering if any of those experiences will get worse. I am planning a trip in the Fall and would like to be prepared... Read more »

New Drug Fuzeon

Posted by Anonymous, 1 Reply
There's a lot of talk about "Fuzeon", a breakthrough fusion inhibitor. It has passed the clinical trial stage and is now in commercial production stage. Lately there has been talk about Roche/Trimeris not being able to make the numbers, due to a... Read more »