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Fosamprenavir Facts

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AIDS InfoNet

Amprenavir (Agenerase)

What Is Amprenavir? Amprenavir is a drug used as part of antiretroviral therapy (ART). It is also called Agenerase ® . It was manufactured by GlaxoSmithKline. Manufacture of amprenavir was discontinued in October 2007. It is being replaced by fosamprenavir (see Fact Sheet 448 ). Fosamprenavir is a pro-drug of amprenavir. This means that when fosamprenavir is taken, it is broken down to produce amprenavir.
Ask the Experts

Tenefovir, Emtriva and Fosamprenavir for wild type virus

Would Teneforvir, Emtriva and Fosamprenavir(not boosted with Retonavir) be a potent combo for myself who is found to carry wild type virus? The present regimen includes Kaletra and Retonavir which is giving me endless GI problems. I am...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post.Though not (yet) formally tested, the combination of tenofovir (Viread), FTC (Emtriva; also available in combination with tenofovir as Truvada) with unboosted fosamprenavir (Lexiva, Telzir) should be quite well tolerated.A... Read more »

STARTING TREATMENT

Hi Ben.As a guy living in the UK, if starting treatment with a CD4 count of less than 200, would you recommend starting with either a Combivir/Sustiva or Truvada/Sustiva combination?Combivir/Sustiva seems to be the most highly recommended of all the...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Dear FG-Thank you for your post-- it's nice to hear from patients in the UK. While our site is based primarily in the US, clearly our comments (and language) apply readily in the UK as well.We're all the benefactors of having some really good... Read more »

Switching to Lexiva/Telzir, Norvir and Truvada

Two years ago I've started taking Kaletra and Combivir. It works very fine for me, nearly without any side effects, my virus load is undetectable and my CD4-count raised from 150 up to 430. Unfortunately my cholesterol levels are relatively high so...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post and kind words.With the arrivals of atazanavir (Reyataz) and fosamprenavir (Lexiva, Telzir), we're seeing a resurgence in the use of first-line protease inhibitors.The proposed regimen of fosamprenavir/ritonavir with Truvada... Read more »

fosamprenavir and tenofovir interaction

Is there any drug-drug interactions that you know of between the new PI- fosamprenavir and tenofovir?
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your question.We have very good data about the one-way interaction-- there's no significant change in fosamprenavir's levels when dosed with tenofovir. This is different that the situation for another new PI, atazanavir. When atazanavir... Read more »
Articles
AIDS InfoNet

Fosamprenavir (Telzir, Lexiva)

What Is Fosamprenavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Fosamprenavir? Fosamprenavir is a drug used for antiretroviral therapy... Read more »
AIDSinfo

An Overview of Lexiva (Fosamprenavir, Telzir)

FOS-am-pren-a-veer Brand Name: Lexiva Other Name(s): Fosamprenavir calcium, GW 433908, GW433908, Telzir, VX 175, f-APV Drug Class: Protease Inhibitors Fosamprenavir, also known as Lexiva, is a type of medicine called a protease... Read more »
AIDS InfoNet

Delavirdine (Rescriptor)

What Is Delavirdine? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Delavirdine? Delavirdine is a drug used as part of antiretroviral therapy... Read more »
AIDS InfoNet

Drug Names and Manufacturers

Reverse Transcriptase Inhibitors ("Nukes") Non-Nucleoside Reverse Transcriptase Inhibitors Protease Inhibitors Integrase Inhibitors Attachment and Fusion Inhibitors Antisense Drugs Immune Modulators None of these drugs can... Read more »
Connect With Others

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

I'm trying not to scare anyone, but facts are fact

Posted by Anonymous, 6 Replies
In fact I'm not trying to scare anyone, and I don't want to make a kid's game out of the Bulletin Board. I'm just trying to make everyone realize that 99,9% of people doesn't cover all individuals, when talking about tests... I'm sure that 999 of... Read more »

HIV FROM CONDOMS AFER FACT?

Posted by Anonymous, 2 Replies
What are the chances of catching hiv when: You have sex with a male with the condom on, after he cums he pulls the condom off and you play around for around 10 minutes he puts his penis in you for a couple of seconds (about 2 inches)? Read more »

Facts II. WIndow Period

Posted by Anonymous, 3 Replies
Without having to travel so far away, you can find posts of Dr. Santana (The Body Spanish section) where he refers to the window period in a very similar way to what I said before, In one of his posts he says: test at 3 months, at 6 months, at 9... Read more »