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Etravirine Dosing

Here's a taste of what has to offer on this topic:
U.S. Food and Drug Administration

Newly Approved Intelence (Etravirine) Dose May Halve Pill Burden

On December 22, 2010, the Food and Drug Administration approved a new 200 mg Intelence (etravirine) tablet. Intelence was originally approved in 2008, in only a 100 mg tablet formulation. The new 200 mg dosage form can help reduce pill burden for... Read more »
U.S. Food and Drug Administration

Intelence (Etravirine): Pediatric Dosing Recommendations and New Scored 25 mg Tablet for Pediatric Dosing

On March, 26, 2012, the Food and Drug Administration approved dosing recommendations for INTELENCE┬« (etravirine) for treatment-experienced pediatric patients 6 to 18 years of age and weighing at least 16 kg. In addition a new scored 25 mg tablet... Read more »
U.S. Food and Drug Administration

Intelence (Etravirine) Label Updated to Reflect Dosing Data Through 48 Weeks

On November 24, 2009, FDA approved revisions to the INTELENCE (etravirine) labeling to include updated results through 48 weeks of dosing for the two Phase 3 trials TMC125-C206 and TMC125-C216 in treatment-experienced patients. This constitutes the... Read more »
Ask the Experts

Once daily dosing of etravirine (Intelence)?

I was on Efavirenz and Truvada but recently switched to Etravirine and Truvada because of sleep/dream/emotional issues. I saw some research that suggested the 400 mg dose of Efavirine could be taken safely once a day...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
There is a study with a new formualtion of Intelence that would be given once a day. We are waiting for final results and then the new form would have to get approval from the FDA. The current pills should not be taken once a day. Stay tuned.Joe... Read more »


Hello, I am positive for almost 8 years now and I have a concern regarding Sustiva (which i have been on since diagnosis). I wanted to know if Etravirine can be used in place of Sustiva (if and when i become resistant to it)? Is this drug only...
David Wohl, M.D.

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill
Etravirine, also known affectionately as TMC125, is a non-nucleoside that is in the last stages of development and is expected to be available in the US within months.Some facts:-Etravirine can be taken with nucleosides.-Some virus that is resistant... Read more »

Etravirine (TMC-125) Clinical Trial?

I was diagnosed in September 2007 and due to my CD4 count going marginally below 350 on 3 consecutive occasions my doctor prescribed Atripla for me 3 months ago. My viral load before medication was around 100,000 copies and my last blood test...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Etravirine can be effective after failing efavirenz based therapy depending on the resistance picture. Use of etravirine may be one reasonable option as would a switch to a boosted protease inhibitor based regimen depending on your entire treatment... Read more »


Hi Dr. Young,Is Etravirine and Nevirapine processed in the same part of the liver? I have been on Nevirapine for 10 years and I amhaving some liver issues. I wonder if Etravirine would use adifferent part of my liver?thanks,tom...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello Tom and thanks for posting.Both medications are processed by the liver, though one generally doesn't distinguish between different parts or cells in the liver with regard to drug metabolism. That said, drug reactions from one medication... Read more »
Connect With Others


Posted by Anonymous, 1 Reply
Hello All !! I want to tell everyone that I started taking half of the prescribed doses of my meds about 2 years ago. My T cells remain High (570) and my V load is still undetectable..
I am on viramune,ziagen and zerit. I had an uncle who died... Read more »

dosing schedule adjustment

Posted by pozartistsd, 1 Reply
hey all you experts out there! I think i may know the answer to this but would like to get some input:

I currently take my meds (Reyataz/Truvada/Norvir) once a day. I take them at 9am (with breakfast, not that you need to know that ) I would like... Read more »

Low-Dose Naltrexone

Posted by renevatio, 1 Reply
Hello all-

I am newly diagnosed, and just getting into the process of researching all about HIV and potential alternative treatments. I am a voracious reader and spend a good bit of time each day reading papers and digging up info on my new internal... Read more »

Skipping Doses

Posted by chrisnxs, 2 Replies
Hello Everyone, can someone please elaborate on the severity of skipping meds? My bf is positive and has been on meds for about a year. He's on my insurance and it kills the price down to a point where he can get his meds pretty easily. I discovered... Read more »