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Efavirenz

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AIDS InfoNet

Efavirenz (Sustiva)

What Is Efavirenz? Efavirenz is a drug used as part of antiretroviral therapy (ART). It is also called Sustiva or Stocrin. It is manufactured by Bristol-Myers Squibb. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (a "non-nuke" or NNRTI). These drugs stop HIV from multiplying by preventing the reverse transcriptase enzyme from working. This enzyme...
Ask the Experts

efavirenz resistance

Hi DocLab tests just resulted in low level resistance to efavirenz. I am currently on truvada and efavirenz. My Doc wants to change to truvada and reyataz. I am concerned about the side effects...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Sorry to hear about the efavirenz (Sustiva) resistance.A switch to truvada + reyatazalone would not be a good move. You would also need to take a small (100 mg)... Read more »

efavirenz or nevirapine

You are all doing a god job with this website.. Thank you so much.I have decided to start treatment with combivir and efavirenz. If i wont be able to tolerate efavirenz can i change to nevirapine or should i first start with nevirapine? My cd4=200...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your questions and comments.You are correct in assuming that if you do not tolerate efavirenz that you could switch to nevirapine. The drugs have different side effect profiles, so a switch for intolerance to one drug... Read more »

alcohol+efavirenz

Puede la ingesta de Sustiva aumentar el nivel de alcohol en sangre y verse reflejado en una prueba de alcoholemia?...
Jorge Santana Bagur, M.D.

Response from Jorge Santana Bagur, M.D.

Universidad de Puerto Rico
En lo absoluto que yo tenga conocimiento.Ninguno de los metabolitos de Sustiva se degradan en azucares que pudiesen convertirse en alcoholes.No tengo seguridad ni he escuchado que Sustiva ni ninguno de los antiretrovirales alteren los resultados de... Read more »

Late night events and Efavirenz

Hey! I recently started my treatment with medicines and I'm taking Efavirenz with Lamivudine and Tenofovir fumarate every day at 11 pm. Thing is, after some time I take the Efavirenz, I start getting some...of normal, but whenever I have some...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Should be able to safely vary timing of efavirenz in the occasional situations you describe so that you alter the dose to fit your actual bedtime so that you are not out and about... in the hours after taking efavirenz. KH... Read more »
Connect With Others

Efavirenz: ways to fight its sleep-reduction.

Posted by BrokenWingedBird, 2 Replies
If Efavirenz (and Efavirenz along)is really wrecking your sleep quality, then the only solution is to stop taking Efavirenz (and substitute it with another drug).

However, there are ways to ensure your sleep is as good as possible.

Important discovery: Read more »

Cost of Combivir (Duovir) and Cost of efavirenz(Sustiva) in Canada

Posted by raj1984, 1 Reply
Hey pals this is urgent , I need to know the cost of Combivir and Sustiva in Ontario (CANADA) . Please quote the price of Brand and not Generic . This is very urgent I am need to submit to immigration lawyer. Read more »

Cost of Combivir (Duovir) and Cost of efavirenz(Sustiva) in Canada

Posted by raj1984
Hey pals this is urgent , I need to know the cost of Combivir and Sustiva in Ontario (CANADA) . Please quote the price of Brand and not Generic . This is very urgent I am need to submit to immigration lawyer. Read more »