Advertisement

The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol

Efavirenz Dosages

Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
AIDS InfoNet

Efavirenz (Sustiva)

What Is Efavirenz? Efavirenz is a drug used as part of antiretroviral therapy (ART). It is also called Sustiva or Stocrin. It is manufactured by Bristol-Myers Squibb. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Efavirenz is a non-nucleoside reverse transcriptase inhibitor (a "non-nuke" or NNRTI). These drugs stop HIV from multiplying by preventing the reverse transcriptase enzyme from working. This enzyme...
Ask the Experts

Efavirenz and Rifafour interaction?

I was just diagnosed with HIV, CD4 count of 4, and although no TB was found, my doctor suspected I have it. I have completed about 1 week of therapy. I am on 4 tabs of Rifafour/day and Combivir and 600mg of Efavirenz. Should my dosage of Efavirenz...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
Hello and sorry to hear about your recent HIV diagnosis. Rifampicin is the main ingredient in rifafour that interacts with Efavirirz (Sustiva). Drug-drug interaction studies showed about a 20% reduction in Efavirenz blood levels from Rifampin. A... Read more »

Dizzy from Efavirenz

I've been on a combination of Combivir & Efavirenz for 3 months and am very happy with the results: Viral Load has gone from >75,000 to <40 & T4 have increased from 180 to 431. So I am not looking to change this cocktail. However...
Andrew T. Pavia, M.D.

Response from Andrew T. Pavia, M.D.

University of Utah, School of Medicine
Mark,Side effects that persist for 3 months can be tough to get rid of, as opposed to those you have in the first few weeks. If you haven't already tried it, try moving your efavirenz dose up in the evening perhaps to dinner time, or even... Read more »

Truvada/Efavirenz:Severe breathing difficulty & racing heartbeat

Dear Doctors, Started takinng Truvada/Efavirenz for a month now and dizziness in the mornings, insomnia, being unseady on my feet and rash on my arms and chest (for few days) were some of the main side effects during the first two weeks. However, I...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Assuming that your cardiac and lung exams have not revealed any clear problems some of your symptoms could be due to the central nervous system effects of Sustiva (some patients can rarely experience severe anxiety/panic attacks with... Read more »

Switching from efavirenz

Hi,Some background:I'm a 26 year old male, positive for almost five years. I was diagnosed during seroconversion & took Kaletra & Combivir for six months. My numbers were then good until early last year, when VL jumped from <10k to...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
The side effects are significant enough for you to consider changing therapy. The level of 4,900 is a typical trough level of Sustiva and well above the inhibitory concentration need to suppress viral replication. The most logical thing I think... Read more »
Connect With Others

Cost of Combivir (Duovir) and Cost of efavirenz(Sustiva) in Canada

Posted by raj1984, 1 Reply
Hey pals this is urgent , I need to know the cost of Combivir and Sustiva in Ontario (CANADA) . Please quote the price of Brand and not Generic . This is very urgent I am need to submit to immigration lawyer. Read more »

Efavirenz: ways to fight its sleep-reduction.

Posted by BrokenWingedBird, 2 Replies
If Efavirenz (and Efavirenz along)is really wrecking your sleep quality, then the only solution is to stop taking Efavirenz (and substitute it with another drug).

However, there are ways to ensure your sleep is as good as possible.

Important discovery: Read more »

Cost of Combivir (Duovir) and Cost of efavirenz(Sustiva) in Canada

Posted by raj1984
Hey pals this is urgent , I need to know the cost of Combivir and Sustiva in Ontario (CANADA) . Please quote the price of Brand and not Generic . This is very urgent I am need to submit to immigration lawyer. Read more »