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Does Atripla Contain A Protease Inhibitor

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AIDS InfoNet

Protease Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Protease Inhibitors These drugs block the protease enzyme. When new viral particles break off from an infected cell, protease cuts long protein strands into the parts needed to assemble a mature virus. When protease is blocked, the new viral particles cannot mature. Protease Inhibitors in Development Several firms are trying to develop a new...
Ask the Experts

Do protease inhibitors cure or just postpone?

I have read several of you're articles and would be extremely grateful if you could answer a few questions. First, do you feelHMO's and other managed care organizations should include such treatments as protease inhibitors in there plans?...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
First, let me answer the question you posed in the title of your question: do protease inhibitors cure HIV disease or delay progression? We know that all antiretroviral therapy delays progression (and death), and that the more effective the... Read more »

new protease inhibitor

I am on a isentress, selzentry and reyataz, norvir regimen and my hepatitis dr wants to me to start the new protease inhibitor for hepatitis. will any of my HIV drugs will interfere with the new Hepatitis medication?Thank you very much...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
You ask an excellent question. Telaprevir is under study right now in combination with pegylated interferon and ribavirin among HIV/HCV coinfected patients. The preliminary results show that the majority of patients are achieving viral suppression... Read more »

Protease Inhibitors

Why are PI's used sometimes in first line therapy ?...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post.Every patient brings individual sets of needs and concerns to the clinic. We always try to have a discussion about the risks and benefits of current DHHS and IAS-USA recommended treatments. There are a number of reasons why... Read more »

Double protease inhibitor regime?

If resistent to all transcriptase inhibitors but to none of protease inhibitors, what would you think of a double protease inhibitor and new Tenofovir regime? Would it be potent enough?, as it is usually the other way around; 1 p.i. and 2 t.i.....
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Studies over the past 5 years have shows pretty clearly that a double PI combo - especially one that has the "booster" impact of ritonavir included - can do well. The primary data of this comes from the combo of just ritonavir and... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

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