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Didanosine

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Get the Facts
AIDS InfoNet

Didanosine (Videx, ddI)

... What Is Didanosine? Who Should Take Didanosine? What About Drug Resistance? How Is Didanosine Taken? What Are the Side Effects? How Does Didanosine React With Other Drugs? What Is Didanosine? ddI (Videx) is a drug used as part of... antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb and by Barr Laboratories. Didanosine is also known as ddI or dideoxyinosine. Generic versions have been tentatively...
Ask the Experts

Vision Changes with Didanosine

...vision requiring new prescription eye wear does not happen suddenly. Can you give any feed back to this being connected to Didanosine. The manufacturers warning label specifically states that one is supposed to bring this to the attention of...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
...prescription lenses can occur quickly at some ages (esp mid-40s). This is a change in lens shape. Reports mostly with high doses of ddI of visual changes were related to retinal (back of the eye) problems and were generally reversible on drug... Read more »

neuropathy pain (didanosine+stavudine+efavirenz)

...won't get bored. I'd really really appreciate your help, time and patience!My question is:My father CD4 recently = 480He is on Didanosine 250mg (in the morning before food),Stavudine 30mg ( 1 tablet twice daily) and Efavirenz 600mg (1 tablet...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hi Tom,Didanosine (ddI) plus stavudine (d4T) is no longer a recommended combination! It has been found to be less effective and substantially more Read more »

zidovudine, didanosine, kaletra

Is the above combination suitable for one considered to be resistant to combivir and effavirenz? I have come across these in the internet. My doctor thinks I could be resistant to combivir and effavirenz. I have been on them for 2 years. Due to...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,Ideally speaking, if resistance develops to a HAART (highly active antiretroviral therapy) regimen, I recommend getting a resistance test to help guide the choice of the next regimen. If resistance testing is not an option in Zimbabwe and your... Read more »

DIDANOSINE

Could ddI chewable tablets be taken once a day?
Judith A. Aberg, M.D.

Response from Judith A. Aberg, M.D.

Washington University, St. Louis School of Medicine
Yes, but only the 200 mg tablet can be used because of the amount of buffer in the tablet. Videx does come in a new capsule formulation which is made for once daily dosing. Unless you have difficulty swallowing capsules, you may want to consider... Read more »
Articles
AIDSinfo

An Overview of Videx (Didanosine, ddI)

...BRN 3619529, CCRIS 805, Didanosina, Dideoxyinosine, HSDB 6548, ddI Drug Class: Nucleoside Reverse Transcriptase Inhibitors Didanosine, also known as ddI or Videx, is a type of antiretroviral drug called a nucleoside reverse transcriptase... Read more »
U.S. Food and Drug Administration

Important Changes to Videx (Didanosine) Labeling

...remove statements for dose reductions for adverse events such as pancreatitis or peripheral neuropathy. Dose reductions for didanosine other than for weight have not been established. In the Videx pediatric powder package insert, Section 2.3... Read more »
U.S. Food and Drug Administration

Videx EC/Videx (Didanosine) Label Change Reflects Potential for Serious Liver Disorder

...rare, but serious, complication in the liver known as non-cirrhotic portal hypertension in patients using Videx or Videx EC (didanosine). Didanosine is a medication used to treat human immunodeficiency virus (HIV) infection. Non-cirrhotic... Read more »
U.S. Food and Drug Administration

Early Communication About an Ongoing Safety Review of Ziagen (Abacavir) and Videx (Didanosine)

...nucleoside reverse transcriptase inhibitors (NRTIs). The NRTIs included in the analyses were zidovudine, stavudine, abacavir, didanosine, and lamivudine. No analyses were conducted evaluating the risk of heart attack when patients take tenofovir... Read more »
Connect With Others

Early HIV Treatment Failure Linked to Didanosine/T

Posted by TwinsDad, 1 Reply
...NEW YORK (Reuters Health) Aug 23 - The combination of the antiretroviral agents didanosine, tenofovir, and efavirenz is associated with a high virological failure rate in treatment-naive patients with HIV, British investigators...had planned a... Read more »

Bristol Myers Squibbs: Videx

Posted by Anonymous, 2 Replies
Gentlemen, Stay away from Videx it infected my pancreas and made me diabetic, apprantly it does that to a high percentage of people on it or as I also understand kills another hign percentage of them. What does Bristol Myers Squibbs do? Sell death... Read more »

Urge segunda opinion

Posted by Edy, 1 Reply
...El problema es que me hicieron un genotipo y segun el resultado sali resistente a: Efavirenz Nevirapine Lamivudine Didanosine Abacavir Emtricitabine Mi doctora me pinto un panarama muy pesimista y medijo que solo tengo una opcion de esquema:... Read more »

50% of HIV+ Develop Neurocognitive Impairment

Posted by ScotCharles, 3 Replies
...were related, to some degree, to the kinds of specific treatments they received, such as a type of drug called the "D" drugs [didanosine (ddI, Videx) and stavudine (d4T, Zerit)]. Coming back to the brain involvement, we also tried to look at... Read more »