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Darunavir Facts

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AIDS InfoNet

Darunavir (Prezista)

What Is Darunavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Darunavir? Darunavir is a drug used as part of antiretroviral therapy (ART). It is also called Prezista TM and used to be called TMC114. It is manufactured by Tibotec Pharmaceuticals. Darunavir is a protease inhibitor. These drugs prevent the protease enzyme from working....
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Darunavir, Ritonavir and Augmentin

I have been prescribed Augmentin for the treatment of bronchitis. Can this be taken with Darunavir and Ritonavir?
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Generally OK to take darunavir/ritonavir with Augmentin. KH Read more »

Darunavir or not to Darunavir + Low WBC

Hi Joe,I have another question for you. I have recently seen my consultant, and he has suggested changing PI's from Atazanavir to Darunavir. He quotes a few studies that suggest additional benefit for DRV. At the moment I'm undetectable on ATV(r)...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Michael,Thanks for your questions. Darunavir is now approved for both first line treatment as well as for treatment experienced patients. It is a very potent protease inhibitor, but potency does not seem to be an issue with your regimen since you... Read more »

Mental-health effects of Truvada/Isentress combination?

For about four months, I've been taking a Truvada-Isentress combination - my first medication after seven years HIV+. My doctor warned me there have been no long-term studies on Isentress' effects, but I agreed to try it anyway. I seem to be...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
There have been a few causes of depression seemingly triggered after starting raltegravir (4 cases reported from Vancouver, BC in the journal AIDS-see below for the authors comments on those cases).epression and other psychiatric adverse events in... Read more »

Concerned with Darunavir dosage

Dear Docs, I am a hospital pharmacist who does a lot of HIV care and meds review and came across a patient with a dose of Darunavir that I can't make sense of. The pt is on Etravirine, Lamivudine, Raltegravir with correct dosing, and boosted...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Dear Stephan,I wish there were more hospital pharmacists like you who really look into the doses and use of antiretrovirals. I agree I cannot think of any data to suypport the dose. The usual dose of darunavir here would be 600 mg twice daily. ... Read more »
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AIDS InfoNet

Drug Names and Manufacturers

Reverse Transcriptase Inhibitors ("Nukes") Non-Nucleoside Reverse Transcriptase Inhibitors Protease Inhibitors Integrase Inhibitors Attachment and Fusion Inhibitors Antisense Drugs Immune Modulators None of these drugs can... Read more »
AIDSinfo

An Overview of Prezista (Darunavir, TMC114)

dar-UE-na-vir Brand Name: Prezista Other Name(s): TMC 114, TMC114 Drug Class: Protease Inhibitors Darunavir, also known as Prezista or TMC114, is a type of medicine called a protease inhibitor (PI). Darunavir... Read more »
AIDS InfoNet

U.S. Antiretroviral Therapy Guidelines

Why Do the Guidelines Keep Changing? Viral Load and CD4 Cell Testing Resistance Testing When to Start Treatment Goals of Therapy What Drugs Should Be Used First? Interrupting Treatment When to Change What to Change To? Why... Read more »
AIDS InfoNet

What Is Antiretroviral Therapy (ART)?

What Is ART? What Is the HIV Life Cycle? Approved ARV Drugs How Are the Drugs Used? What Is Drug Resistance? Can These Drugs Cure AIDS? When Do I Start? Which Drugs Do I Use? What's Next? What Is ART? ART means treating... Read more »
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Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

Lost

Posted by LostNconfused, 5 Replies
I tested positive 3 days before Christmas and I think I am still numb to the fact. I haven't told any friends or family because I really don't know how and most are judgemental and I'm sure will walk away. But I guess if they do, then I didn't need... Read more »

Cant seem to get to undetectable

Posted by Weekev, 5 Replies
Hi Guys! Ive been on Meds for 7months now but just cant get to undetectable! My adherence is perfect never even been late as is my diet and excercise! Has anyone else experienced this problem?. I switched from Sustiva/Truvada after 5months to... Read more »

testing info

Posted by Anonymous
Search Our Site Enter Keywords or Fact Sheet Number: Revised January 10, 2006 Hojas Informativas en Espaol: Newest Fact Sheets 128. Body Composition Tests 157. Microbicides 158. AIDS Myths and Misunderstandings 408.... Read more »