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Darunavir Dosing

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Get the Facts

An Overview of Prezista (Darunavir, TMC114)

dar-UE-na-vir Brand Name: Prezista Other Name(s): TMC 114, TMC114 Drug Class: Protease Inhibitors Darunavir, also known as Prezista or TMC114, is a type of medicine called a protease inhibitor (PI). Darunavir works by blocking protease, an enzyme that HV needs to make more copies of itself. During the normal HIV life cycle, an HIV enzyme called protease cuts long chains of HIV proteins into smaller...
Ask the Experts

Duranivir (Prezista) new strength pills and resistance risks

I am currently on Truvada (1 450mg daily), Prezista (3 x 300mg daily) and Norvir 100mg. Viral load is undetectable and t cell count at 144 since diagnosed in Dec 2008.My most recent prescription now incorporates the new strength Prezista pills as...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for your post.There are two different dosing strategies for darunavir (Prezista)- for persons who are treatment experienced (namely with protease inhibitor resistance), the medication should be dosed 900 mg twice daily with 100 mg... Read more »

Concerned with Darunavir dosage

Dear Docs, I am a hospital pharmacist who does a lot of HIV care and meds review and came across a patient with a dose of Darunavir that I can't make sense of. The pt is on Etravirine, Lamivudine, Raltegravir with correct dosing, and boosted...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Dear Stephan,I wish there were more hospital pharmacists like you who really look into the doses and use of antiretrovirals. I agree I cannot think of any data to suypport the dose. The usual dose of darunavir here would be 600 mg twice daily. ... Read more »

side effects

i 've been on treatment for about a month plus,i seem to loose appetite most especially early in the mornings when i need to eat before taking my meds
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for your post.Several HIV medications should be taken with food-- including atazanavir (Reyataz) and darunavir (Prezista). Anorexia can be a problem for patients who have this dosing requirement. First, it's important to let your... Read more »

whts the best form of treatmnet?

pls wht is the best treatment for a person esp if this person` used io magnetic tablets from before.?generally hats the best treatment now?
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Thanks for the post. Treatment should be planned for each person, there is no cookbook. That is one size does not fit all. A test for drug resistance should be done first. Assuming that it shows no resistance in your virus to any medication, the... Read more »
AIDS InfoNet

Darunavir (Prezista)

What Is Darunavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Darunavir? Darunavir is a drug used as part of antiretroviral therapy... Read more »
U.S. Food and Drug Administration

HIV/AIDS Update - Important information about Prezista (darunavir)

This message describes the following important changes affecting Prezista (darunavir) Traditional approval of Prezista New dosing regimen for treatment-na├»ve patients New 400 mg tablets Revised Pregnancy Category On October 21, 2008, FDA... Read more »
Canadian AIDS Treatment Information Exchange

Odin -- Darunavir-Ritonavir Once or Twice Daily

Darunavir (Prezista) is a protease inhibitor that is an effective part of HAART when prescribed at a dose of 600 mg, taken with 100 mg of ritonavir (Norvir), both drugs taken twice daily. The presence of ritonavir raises and prolongs the levels... Read more »
Canadian AIDS Treatment Information Exchange

Monotherapy With Darunavir-Ritonavir -- the Monet Study

In December 2009, the U.S. Department of Health and Human Services (DHHS) updated its guidelines for the treatment of HIV-positive people. These guidelines recommend specific regimens (which the DHHS calls "preferred" regimens) for doctors and... Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

Prezista + Norvir + Truvada

Posted by notreadyforthis, 1 Reply
So I took my first dose of meds last night. My doctor started me on this combo: Prezista (darunavir), two 300mg tabs, plus Norvir (ritonavir), one 100mg soft gelcap, plus Truvada (emtricitabine+tenofavir) one 200mg/300mg respectively. I take this... Read more »

Excessive Mastubation

Posted by Anonymous, 5 Replies
Ever since I found out that I'm poz, I've been spending a lot more time mastubating. Is that normal? Or could it be because of the amount of time I've been spending reading posts about sexual issues? Pleasing myself has become an every day thing... Read more »

Two weeks down and a life time to live

Posted by trulife, 2 Replies
Well's the end of two weeks on Atripla and so far things are going well. Side effects have been limited and are now subsiding. My biggest problem so far is swallowing the pill. I have always had trouble swallowing pills...go figure...a... Read more »