Celsentri

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An Overview of Selzentry (Maraviroc, Celsentri)

mah-RAV-er-rock Brand Name: Selzentry Other Name(s): Celsentri, MVC, UK-427,857 Drug Class: Entry and Fusion Inhibitors Maraviroc, also known as Selzentry, is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking HIV from entering human cells. Indications and Usage Maraviroc received accelerated approval on August 6, 2007, and traditional approval on November 25, 2008, by the FDA for the treatment...

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Question about Selzentry's side effects?

`My doctor wants to put me on Selzentry/Celsentri. He says that he has had very good immunological responses in his patients, compared with other drugs. Initially I would be on...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

Hello Thank you for your questions.The use of Selzentry (or Maraviroc) is a novel approach to treat HIV infection. There are ongoing discussions about using this drug as part of an initial regimen to treat HIV infection. Before one can use this... Read more »

NEW DRUGS

Dear Dr. Frascino,I have been following the question+answers on the forum since I was diagnosed HIV+ close to 2 years ago. I particularly like the positiveness and good humor in your answers. Well, getting back to my case, I am 46 years old and was...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

agents to have made it out of the development pipeline are (1) Pfizer's CCR5 antagonist maraviroc ("Selzentry" in the U.S. and "Celsentri" elsewhere in the world) and (2) Merck's integrase inhibitor Raltegravir (Isentress). Looking farther into the... Read more »

Naive but bad genotype. Which combo ?

Hello,I would like to thank you for your forum, which is very helpful !My question is the following:I have probably been infected Q4 2006 and discover it on Sept 2006. I have no symptoms in the exception of swollen lymph nodes. The PET-scan showed...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Good questions. We don't yet know the best manner/order to use the new Merck integrase inhibitor raltegravir, the CCR5 inhibitor maraviroc, Fuzeon, and etravirine (NNRTI active against R virus now available in the US through expanded access... Read more »

Diet and lipohypertrophy

Dear Nelson,I have a question regarding reducing lipohypertrophy with diet. I am a 50-year-old man, tested positive for HIV in 1985, started meds (AZT, 3TC and Crixivan) in 1996, switched meds last year (2007) to Lexiva/Norvir/Combivir. I am gluten...

Response from Nelson Vergel, B.S.Ch.E., M.B.A.

Program for Wellness Restoration

Dear MarkYou have been exposed to one of the combinations that has been shown to cause more metabolic disorders than most for a long time. Crixivan is well known to cause insulin resistance and AZT is well known to cause lipoatrophy. The two... Read more »

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Articles

Maraviroc (Selzentry, Celsentri)

What Is Maraviroc? Who Should Take It? What About Drug Resistance? How Is Maraviroc Taken? What Are the Side Effects? How Does It React With OtherDrugs? The Bottom Line What Is Maraviroc? Maraviroc (Selzentry in the US and... Read more »

Maraviroc (Selzentry, Celsentri)

¿Qué Es Maraviroc? ¿Quién Debe Tomar Maraviroc? ¿Qué Es la Resistencia a los Medicamentos? ¿Cómo se Toma Maraviroc? ¿Cuáles Son los Efectos Secundarios? ¿Cómo Reacciona Maraviroc con Otros Medicamentos? En Pocas Palabras... Read more »

FAQs About Selzentry (Maraviroc, Celsentri) From The Body's "Ask the Experts" Forums

Basics | Tropism Testing | Drug Resistance | Side Effects Basics Is Selzentry appropriate for someone just starting HIV medications or is it only for medication experienced patients? Will the new drugs like Selzentry work as well in... Read more »

U.S. Centers for Disease Control and Prevention

New Drug Approved in Canada to Treat HIV, First in 10 Years

On Monday, Pfizer Canada Inc. announced that its CCR5 co-receptor antagonist, Celsentri (maraviroc), was approved by Health Canada for use in treatment-experienced patients with HIV resistant to existing therapies. It is not licensed for use as a... Read more »

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