Can Isentress Be Taken Once Daily

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Ask the Experts

Isentress once daily?

Hi,My first (and current) meds are Truvada + Isentress, on which my doc started me around August of 2009. At that time he said that there was a current study to determine if the Isentress could be taken in once-a-day dosing (both 400mg tabs taken...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello and thanks for your post.While raltegravir (Isentress) has proven itself to be a very potent and well tolerated medication and now recommended as part of US treatment guideline first-line treatments, the recently concluded QDMRK study showed... Read more »

how to switch from daily dose of Isentress to twice daily

I've been taking Truvada and Isentress for the past 18 months with great... Read more »

Response from Benjamin Young, M.D., Ph.D. »

once daily isentress and truvada

Hi Dr Mark,l am waiting to begin a once daily trial for efective use of isentress and truvada...do... Read more »

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C. »

Go to Ask the Experts »

Articles

U.S. Centers for Disease Control and Prevention

Merck's HIV Drug Isentress Fails Once-a-Day Study

Taking the HIV drug Isentress once a day is not as effective as the standard twice-daily regimen, reported drug manufacturer Merck & Co. Based on these initial results, Merck is suspending the Phase III trial of once-daily dosing. Isentress is... Read more »

Switching Isentress to Once a Day Is Less Effective

Although the integrase inhibitor Isentress (raltegravir) is recommended for people going on treatment for the first time, it's the only first line drug that's taken twice, not once, a day. In an effort to simplify the dosing, a study compared taking... Read more »

Once-Weekly and Once-Monthly HIV Meds in the Pipeline: Studies From ICAAC 2012

Two new HIV drugs in development that show promise for less frequent dosing were previewed at ICAAC 2012 in San Francisco. One of the drugs, a fusion inhibitor named albuvirtide, could make once-a-week HIV medication a reality. Results from two... Read more »

Study Supports Use of Isentress for First-Line Treatment

A study presented at the joint 2008 ICAAC / IDSA in Washington, DC found that Isentress (raltegravir) was equally potent and better tolerated than Sustiva (efavirenz) when used as part of a person's first HIV regimen. While it's unlikely to greatly... Read more »

Connect With Others

Complera, the new once-daily combo pill

Posted by bartleby

new treatment option. here's what you need to know.
Complera (rilpivirine/tenofovir/FTC) is like Atripla (efavirenz/tenofovir/FTC) except it replaces the Sustiva (efavirenz, Stocrin) arm with Edurant (rilpivirine). it has to be taken with a meal.... Read more »

Isentress in hiv negative woman

Posted by Samantha, 2 Replies

Hello.. I'm HIV negative, but I'm considering enrolling in a study that uses Isentress to determine: if twice daily dose of raltegravir results in drug concentration levels in the female genital tract that are sufficient enough to block HIV-1... Read more »

anyone taking Isentress and Invirase combination?

Posted by nevereasy

Isentress is a relatively new therapy. My Dr just added it to my mono therapy of Invirase (boosted with Norvir). I have been undetectable for two years on the Invirase but my Tcells never get over 300. He added Isentress. I have had bad reflux ( not... Read more »

Itchy bumps on face--On Isentress,Prezista,Norvir

Posted by llee, 2 Replies

Hi all,

my doctor put me on a combo of Isentress,Prezista,Norvir in June. Soon after I started I got itchy bumps all over my face, and also on my neck and upper chest and upper arms. According to the doctor it's because of Immune Reconstitution... Read more »

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