Atazanavir Dosing

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Get the Facts

Atazanavir (Reyataz)

What Is Atazanavir? Atazanavir, also called Reyataz, is a drug used as part of antiretroviral therapy (ART). Atazanavir is a protease inhibitor manufactured by Bristol-Myers Squibb. Atazanavir was approved by the FDA in 2003. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Protease inhibitors prevent the protease enzyme from working. HIV protease acts like a chemical scissor. It cuts the raw material for HIV...

Ask the Experts

Low trough level Atazanavir

I have been on a combination of Atazanavir 500 mg. Ritonovir 100mg and nevirapine 400 mg for two years. Despite a consistently very low blood serum trough level for Atazanavir my viral load has remained undetectable and tcells increased by 100 to...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

You are a "fast" metabolizer of atazanavir because the nevirapine is causing you to metabolize the atazanavir faster and ritonavir boosting is not able to overcome this. Sustiva and viread would probably result in the same effect. Is there... Read more »

drug that fixes atazanavir problem

Dr. Young,Are researchers working on some drug that fixes the flaw in atazanavir. For instance, you take it and can be assured the yellowing effect permanently reverses. If they are not, this might be a great idea. What do you think?Neil...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your question.Elevations in the blood chemical bilirubin occur very commonly among person who take the new protease inhibitor atazanavir (Reyataz). Very significant elevations can occur in about a third of persons who take the drug... Read more »

re yellow eyes atazanavir /and facial wasting.

Hi Doctor. I have been getting yellowing of the eyes (and skin to a degrree) with atazanavir. I switched to Darunavir 800mg a day and experienced facial wasting which I have had in the past and have been getting scupltra for . Should I go back to a...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

Dear John,Darunavir should not have caused facial wasting. That would be highly unusual and such facila wasting typically takes a long time to develop. I wonder if your Sculptra was wearing off. I would not use 600mg once a day. Atazanavir can... Read more »

Atazanavir/reyataz + "yellow fever"

hi docs,I'm 41F, hiv+ 18 years and on meds for 10. I Spent the last four months on kaletra suffering from constant nausea. I should've taken shares in the company that makes vomex - lol. Adherence has never been a problem for me...my...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Perhaps 5% of patients on atazanavir develope severe elevation in their bilirubin that are not acceptable. It is less clear to me what the percent is for patients on boosted atazanavir (with low dose ritonavir) though may be somewhat higher. Modest... Read more »

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Those taking, Raltegravir, Truvada & Atazanavir

Posted by sweetvanilla27, 1 Reply

I am wanting to hear from anyone who have experienced taking Raltegravir, Truvada & Atazanavir and how you have got on with the meds?

I first started taking meds in May this year I was put on Truvda and Sustiva first, and was taken off them due... Read more »

need atazanavir

Posted by princealbert

Does anyone know how to access atazanavir, a new protease inhibitor not yet approved? I've got less than 20 CD4, VL 40,000, am multi-drug resistant, and don't have too many options left. I might be getting T-20, but need another good drug to add to... Read more »

Need Atazanavir

Posted by princealbert, 1 Reply

HALF DOSING MY MEDS

Posted by Anonymous, 1 Reply

Hello All !! I want to tell everyone that I started taking half of the prescribed doses of my meds about 2 years ago. My T cells remain High (570) and my V load is still undetectable..
I am on viramune,ziagen and zerit. I had an uncle who died... Read more »

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