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3TC Dose

Here's a taste of what has to offer on this topic:
HIV i-Base

Dose Optimisation: 50 mg Ritonavir-Boosting, 3TC Dosing and Raltegravir Once-Daily

The issue of dose optimisation is important for several reasons, ranging from finding the right dose for an individual patient that achieves the highest probability of therapeutic success with the lowest risk of adverse events, to as a strategy to... Read more »

An Overview of Epivir (3TC, Lamivudine)

la-MI-vyoo-deen Brand Name: Epivir Other Name(s): 3TC Drug Class: Nucleoside Reverse Transcriptase Inhibitors Approved Use: Treatment of HIV Infection WARNING: Lamivudine can cause serious, life-threatening side effects. These... Read more »

An Overview of Trizivir (AZT/3TC/Abacavir)

a-BAK-a-veer, la-MI-vyoo-deen, zye-DOE-vyoo-deen --> Brand Name: Trizivir Other Name(s): ABC/3TC/ZDV, abacavir sulfate/lamivudine/zidovudine Drug Class: Nucleoside Reverse Transcriptase Inhibitors Approved Use: Treatment of HIV... Read more »
Ask the Experts

Combining Lipitor and d4t/3tc?

d4t/3tc3:30P Crix6:00P Lipitor11:30P Crix/d4t/3tcMy question is, can I combine my Lipitor with the 11:30A d4t/3tc dose?Thanks for your thoughts.S in Los Angeles...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Many cholesterol lowering statins are supposed to be taken in the evening. The logic for this is that the enzyme they inhibit, HMGCoA, does most of its work at night synthesizing cholesterol. The manufacturer of lipitor does not push this as an... Read more »

Neuropathy in legs and 3TC?

I've been positive for probably over 20 years and on meds for 8 years. Currently on atazanavir, abacavir and 3TC once a day, undetectable (for 7+ years) and CD count around 6-700. Had neuropathy when diagnosed in 1996 from HIV which declined...
Brian Conway, M.D.

Response from Brian Conway, M.D.

University of British Columbia
It is highly unlikely that the once daily dose of lamivudine makes any difference in the side effect profile of this drug, which is quite benign to begin with. Over the past 12 years, I have only ever encountered a single case of neuropathy that... Read more »

Combivir totally equivalent to AZT + 3TC?

Is Combivir completely equivalent to taking AZT and 3TC separately? I suppose when taken separately, the proportion could be changed (more of one or the other) whereas the propotion is fixed in Combivir, right? Any other reason why the separate...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
No, combivir has been shown in several studies to be comparable to zidovudine and lamivudine dosed seperately.So, if you are taking zidovudine and lamivudine as part of your antiretroviral regimen, it makes sense to take combivir.... Read more »

Insomnia and 3tc

DoctorI am having trouble staying asleep. This started about 4 mths ago after returning from overseas. Initially I thought it was the time change and tried melatonin. That worked for 6 wks only. I understand it could be the 3tc medication. But wht...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Tough situation to pin on 3TC given the scenario you described. It would be unusual for 3TC to be the main culprit though it could happen (switching to a different med for 1-2 months would sort that out such as tenofovir or abacavir). Given that... Read more »
Connect With Others

Reyataz,Norvir, Kivexa [abacavir/3TC, Epzicom].

Posted by Mondo
Is there anyone here at the forum taking the following cocktail?
I'm taking Reyataz[atazanavir], Norvir [ritonavir] and Kivexa [abacavir/3TC, Epzicom]. I would be interested to know how you are going with it and any problems or side effects that you... Read more »


Posted by Anonymous, 1 Reply
Hello All !! I want to tell everyone that I started taking half of the prescribed doses of my meds about 2 years ago. My T cells remain High (570) and my V load is still undetectable..
I am on viramune,ziagen and zerit. I had an uncle who died... Read more »

dosing schedule adjustment

Posted by pozartistsd, 1 Reply
hey all you experts out there! I think i may know the answer to this but would like to get some input:

I currently take my meds (Reyataz/Truvada/Norvir) once a day. I take them at 9am (with breakfast, not that you need to know that ) I would like... Read more »

Low-Dose Naltrexone

Posted by renevatio, 1 Reply
Hello all-

I am newly diagnosed, and just getting into the process of researching all about HIV and potential alternative treatments. I am a voracious reader and spend a good bit of time each day reading papers and digging up info on my new internal... Read more »